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485896

Sigma-Aldrich

L-Asparagine-(amide-15N) monohydrate

98 atom % 15N

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About This Item

線性公式:
H215NCOCH2CH(NH2)CO2H · H2O
CAS號碼:
分子量::
151.13
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.12
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同位素純度

98 atom % 15N

品質等級

形狀

solid

光學活性

[α]20/D +31.5°, c = 1 in 1 M HCl

mp

233-235 °C (lit.)

質量偏移

M+1

SMILES 字串

O.N[C@@H](CC([15NH2])=O)C(O)=O

InChI

1S/C4H8N2O3.H2O/c5-2(4(8)9)1-3(6)7;/h2H,1,5H2,(H2,6,7)(H,8,9);1H2/t2-;/m0./s1/i6+1;

InChI 密鑰

RBMGJIZCEWRQES-UEFLAVRISA-N

相關類別

包裝

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Jun Wu et al.
Nature cell biology, 23(1), 75-86 (2021-01-10)
Nutrient availability is central for T-cell functions and immune responses. Here we report that CD8+ T-cell activation and anti-tumour responses are strongly potentiated by the non-essential amino acid Asn. Increased Asn levels enhance CD8+ T-cell activation and effector functions against
Longfei Deng et al.
Nature communications, 11(1), 1755-1755 (2020-04-11)
Asparagine synthetase (ASNS) catalyses the ATP-dependent conversion of aspartate to asparagine. However, both the regulation and biological functions of asparagine in tumour cells remain largely unknown. Here, we report that p53 suppresses asparagine synthesis through the transcriptional downregulation of ASNS

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