437352

4-吡咯烷-1-基哌啶

95%

• 同義詞: 1-(Piperidin-4-yl)pyrrolidine
• 經驗公式（希爾表示法）: C₉H₁₈N₂
• CAS號碼: 5004-07-9
• 分子量：: 154.25
• EC號碼: 225-676-6
• MDL號碼: MFCD00038011
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24867366
• NACRES: NA.22

屬性

• 化驗: 95%
• 形狀: solid
• mp: 53-56 °C (lit.)
• SMILES 字串: C1CCN(C1)C2CCNCC2
• InChI: 1S/C9H18N2/c1-2-8-11(7-1)9-3-5-10-6-4-9/h9-10H,1-8H2
• InChI 密鑰: STWODXDTKGTVCJ-UHFFFAOYSA-N

描述

一般說明

4-(1-Pyrrolidinyl)piperidine (4-pypp) has been reported to form Hofmann type complexes [M(4-pypp)₂Ni(CN)₄] (M=Ni or Co) and their FT-IR and Raman spectra have been studied.[1] FT-IR, Raman spectra and the vibrational spectra of 4-pypp have been recorded between 4000 and 400cm^-1.[2]

應用

4-(1-Pyrrolidinyl)piperidine was employed for the synthesis of the following analogs:[3]

• 4-pyrrolidin-1´-yl-1-[2-(2″-nitro-phenyl)-2-oxo-ethyl]-piperidinium bromide
• 4-pyrrolidin-1´-yl-1-[2-(3″-nitro-phenyl)-2-oxo-ethyl]-piperidinium bromide
• 4-pyrrolidin-1´-yl-1-[2-(2″,4″-dimethoxy-phenyl)-2-oxo-ethyl]-piperidinium bromide
• 4-pyrrolidin-1´-yl-1-[2-(3″,4″-dihydroxy-phenyl)-2-oxo-ethyl]-piperidinium bromide

Reactant for synthesis of:
Small molecule ligands of methyl-lysine binding proteins
Small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells
Selective Polo-like kinase 1 inhibitors
Molecules with effects on plasma glucose levels
Vasopressin1b receptor antagonists
IKKβ inhibitors

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves