推薦產品
化驗
97%
形狀
solid
mp
43-47 °C (lit.)
SMILES 字串
CC(C)(C)OC(=O)N1CCNCC1
InChI
1S/C9H18N2O2/c1-9(2,3)13-8(12)11-6-4-10-5-7-11/h10H,4-7H2,1-3H3
InChI 密鑰
CWXPZXBSDSIRCS-UHFFFAOYSA-N
尋找類似的產品? 前往 產品比較指南
一般說明
1-Boc-哌嗪是-Boc保护的哌嗪。1-Boc-哌嗪与芳基碘的CuBr/1,1′交叉偶联。研究报道了铋-2-萘酚(催化剂)和K3PO4(碱)。1-Boc-哌嗪与芳基卤化物发生布赫华-哈特威格偶联反应。碘催化无溶剂N-Boc保护可制备80%产率的1-Boc-哌嗪。
應用
1-Boc-哌嗪可用于:
- (m·-苯氧基)苯基取代哌嗪衍生物系列的制备
- 通过活性阳离子开环聚合合成α,β-聚(2-噁唑啉)脂聚合物期间的终止步骤。
- 单取代哌嗪的制备,例如吲唑脱氧核糖核酸回旋酶抑制剂的合成
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
235.4 °F - closed cup
閃點(°C)
113 °C - closed cup
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
客戶也查看了
Bioorganic & medicinal chemistry letters, 14(11), 2857-2862 (2004-05-06)
In this study, we report the design, synthesis and structure-activity relationships of novel indazole derivatives as DNA gyrase inhibitors with Gram-positive antibacterial activity. Our results show that selected compounds from this series exhibit potent antibacterial activity against Gram-positive bacteria including
Bioorganic & medicinal chemistry letters, 22(1), 377-379 (2011-11-29)
There is currently an unmet need for the development of small-molecule therapeutics for norovirus infection. The piperazine scaffold, a privileged structure embodied in many pharmacological agents, was used to synthesize an array of structurally-diverse derivatives which were screened for anti-norovius
Journal of medicinal chemistry, 47(11), 2833-2838 (2004-05-14)
With the aim of identifying structurally novel, centrally acting histamine H(3) antagonists, arrays of monoacyldiamines were screened. This led to the discovery of a series of 1-alkyl-4-acylpiperazines which were potent antagonists at the human histamine H(3) receptor. The most potent
The Journal of organic chemistry, 71(21), 8283-8286 (2006-10-10)
An efficient and practical protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of a catalytic amount of molecular iodine (10 mol %) under solvent-free conditions at ambient temperature is
α,ω-Functionalized Poly (2-Oxazoline) s Bearing Hydroxyl and Amino Functions.
Macromolecular Chemistry and Physics, 212(16), 1815-1824 (2011)
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務