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Merck
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文件

394408

Sigma-Aldrich

1-(溴乙酰)芘

97%

同義詞:

2-Bromo-1-(1-pyrenyl)ethanone

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About This Item

經驗公式(希爾表示法):
C18H11BrO
CAS號碼:
分子量::
323.18
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

形狀

solid

mp

129-131 °C (lit.)

SMILES 字串

BrCC(=O)c1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C18H11BrO/c19-10-16(20)14-8-6-13-5-4-11-2-1-3-12-7-9-15(14)18(13)17(11)12/h1-9H,10H2

InChI 密鑰

KAEDEGFCOPIKKM-UHFFFAOYSA-N

一般說明

1-(Bromoacetyl)pyrene (BAP) is a pyrene derivative. It has been synthesized by reacting cupric bromide with 1-acetylpyrene. Studies suggest that the introduction of a bromoacetyl chromophoric moiety to pyrene drastically increases the photoinitiating efficiency of pyrenes.

應用

1-(Bromoacetyl)pyrene is suitable for use in the following studies:
  • As an initiator in the bulk polymerization of 2-ethyl-2-oxazoline to generate pyrene labelled poly(2-ethyl-2-oxazoline) (PETOX-py).
  • As a fluorophore in the generation of podand-type fluoroionophores with two pyrene moieties.
  • As a fluorescent labeling agent for the determination of okadaic acid toxin by HPLC with fluorescence detection.
It may also be used in the following studies:
  • As a photoremovable protecting group for carboxylic acids and amino acids.
  • As a photoinitiator in the photopolymerization of styrene with methylmethacrylate.
  • As a reactant in the synthesis of potentially tetradentate pyrene appended ligands.
  • As a derivatizing agent of dialkyl phosphates (DAP) in the HPTLC method of quantitative determination of DAP in fruit juices.

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Aquatic Chronic 4 - Eye Dam. 1 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

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Juraj Kronek et al.
Journal of materials science. Materials in medicine, 22(7), 1725-1734 (2011-05-24)
Poly(2-oxazolines) with varying alkyl chain lengths (e.g., methyl, ethyl, aryl) and molar masses have been tested for cell cytotoxicity in vitro. A standard 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used for the estimation of cell viability. Two monomers, 2-methyl-2-oxazoline and 2-ethyl-2-oxazoline
Copolymerization of n-butylacrylate with styrene by a novel photoinitiator, 1-(bromoacetyl) pyrene.
Mishra A and Daswal S
Journal of Applied Polymer Science, 102.4, 3233-3239 (2006)
S S Kelly et al.
Journal of chromatography. A, 749(1-2), 33-40 (1996-10-18)
The rare diarrhetic shellfish toxin, dinophysistoxin-2 (DTX-2), was isolated from the digestive glands of mussels (Mytilus edulis). This was achieved by chromatography on silica and Sephadex LH-20 followed by reversed-phase solid phase extraction and semi-preparative high-performance liquid chromatography (HPLC) with
1-(Bromoacetyl) pyrene, a novel photoinitiator for the copolymerization of styrene and methylmethacrylate.
Mishra A and Daswal S
Radiation Physics and Chemistry, 75(9), 1093-1100 (2006)
H Ochiai et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(1), 211-217 (1997-06-20)
By using a fluorescent derivatization and column-switching technique, a highly sensitive and selective high-performance liquid chromatographic (HPLC) method has been developed for the determination of simvastatin (I, beta-hydroxy-delta-lactone form) and its active hydrolyzed metabolite (II, beta,delta-dihydroxy acid form of I)

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