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重要文件

401633

Sigma-Aldrich

1-芘甲胺 盐酸盐

95%

同義詞:

PMA

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About This Item

經驗公式(希爾表示法):
C17H13N · HCl
CAS號碼:
分子量::
267.75
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

95%

形狀

powder

mp

258 °C (dec.) (lit.)

官能基

amine

SMILES 字串

Cl[H].NCc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C17H13N.ClH/c18-10-14-7-6-13-5-4-11-2-1-3-12-8-9-15(14)17(13)16(11)12;/h1-9H,10,18H2;1H

InChI 密鑰

RGNMXKKNDSHTFD-UHFFFAOYSA-N

一般說明

1-芘乙胺盐酸盐是一种有机构件。

應用

1-芘乙胺盐酸盐 (PyNH 2 ) 已被用于将人端粒酶逆转录酶 (hTERT) 小干扰 RNA (siRNA) 加载到功能化氧化石墨烯 (GO) 中,用于肿瘤靶向递送 siRNA。[1]
1-芘乙胺盐酸盐用于制备 1-芘乙胺。[2]它可用于 SWNT 的非共价功能化,阳离子部分与 DNA 带负电荷的磷酸骨架强烈结合。[3]可用于制备以下席夫碱配体:
  • 芘-1-基甲基-\ [2-(6-{2-\ [(芘-1-基甲基亚氨基)-甲基]-苯氧甲基 }-吡啶-2-基甲氧基)-亚苄基]-胺[4]
  • 2(芘-1-基甲基-{2-\ [6-(2-{\ [(芘-1-基甲基)-氨基]-甲基 }-苯氧甲基)-吡啶-2-基甲氧基])-苄基 }-胺[4]
1-芘甲胺(PyNH2)用于合成下列物质:
  • 芘基透明质酸(Py-HA),一种基于芘基的聚合物,可用于开发pH值触发的药物载体[5]
  • 电化学电极,用于与芘官能化叶酸衍生物结合的还原氧化石墨烯[6]

还可以用于合成4,6-二氯-2--2-芘甲胺-1,3,5-三嗪,这是用于合成星形聚合物4,6-双(9H-咔唑-2-氧基)-2-(芘甲胺)-1,3,5三嗪(TPC)的前体。 [7]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Assembly of chemically reduced graphene oxide with folic acid functionalized with pyrene moieties and electrochemical sensing of folate receptors.
Kwon B, et al.
Carbon Letters, 27(2), 26-34 (2018)
Liwei Hui et al.
ACS nano, 14(10), 13047-13055 (2020-10-14)
We demonstrate area-selective atomic layer deposition (ALD) of oxides on DNA nanostructures. Area-selective ALD of Al2O3, TiO2, and HfO2 was successfully achieved on both 2D and 3D DNA nanostructures deposited on a polystyrene (PS) substrate. The resulting DNA-inorganic hybrid structure
The preparation of functionalized graphene oxide for targeted intracellular delivery of siRNA.
Yang X, et al.
Journal of Materials Chemistry, 22(14), 6649-6654 (2012)
Fabien Giroud et al.
Biosensors & bioelectronics, 87, 957-963 (2016-09-26)
We report the functionalization of multi-walled carbon nanotubes (MWCNTs) electrodes by a bifunctional nitroaromatic molecule accomplished via π-π interactions of a pyrene derivative. DTNB (5,5'-dithiobis(2-nitrobenzoic acid)) has the particularity to possess both electroactivable nitro groups and negatively charged carboxylic groups.
Reactively formed block and graft copolymers as compatibilizers for polyamide 66/PS blends.
Jeon HK, et al.
Polymer, 45(1), 197-206 (2004)

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
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      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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