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Merck
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392588

Sigma-Aldrich

2,2,5,5-四甲基-3-吡咯烷羧酰胺

98%

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About This Item

經驗公式(希爾表示法):
C9H18N2O
CAS號碼:
分子量::
170.25
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

solid

mp

128-131 °C (lit.)

SMILES 字串

CC1(C)CC(C(N)=O)C(C)(C)N1

InChI

1S/C9H18N2O/c1-8(2)5-6(7(10)12)9(3,4)11-8/h6,11H,5H2,1-4H3,(H2,10,12)

InChI 密鑰

POAGFQOGFRYOFM-UHFFFAOYSA-N

一般說明

2,2,5,5-Tetramethyl-3-pyrrolidinecarboxamide (2,2,5,5-Tetramethylpyrrolidine-3-carboxamide) is a carboxamide of hydrogenated pyrrole derivative. Its synthesis by the hydrogenation of 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamide has been reported. The antiarrhythmic activity of some of the derivatives of 2,2,5,5-tetramethylpyrrolidine-3-carboxamide has been evaluated.
2,2,5,5-Tetramethyl-3-pyrrolidinecarboxamide, a pyrrolidine derivative, is a cyclic (five-membered ring) secondary amine having four carbon atoms and one nitrogen atom. Various physical properties (freezing point, boiling point, density and refractive index) of 2,2,5,5-tetramethyl-3-pyrrolidinecarboxamidehave been reported.

應用

2,2,5,5-Tetramethyl-3-pyrrolidinecarboxamide may be used in the synthesis of its nitroxide, 3-carbamoyl-2,2,5,5-tetramethyl-1-pyrrolidinyloxy free radical.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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Nitroxide free radicals in the hydrogenated pyrrole series.
Rozantsev EG, et al.
Russian Chemical Bulletin, 15(4), 638-641 (1966)
Yaws CL.
The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals, 260-260 (2015)
O H Hankovszky et al.
Journal of medicinal chemistry, 29(7), 1138-1152 (1986-07-01)
N-(omega-Aminoalkyl)-2,2,5,5-tetramethyl-3-pyrroline- or -pyrrolidine-3-carboxamides were acylated on the primary amino group of the side chain by means of reactive acid derivatives (acid chlorides, activated esters, phthalic anhydrides, phthalimide, 2-alkyl-4H-3,1-benzoxazin-4-ones) or they were alkylated by forming the Schiff bases and subsequent sodium

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