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349720

Sigma-Aldrich

(3-羧丙基)三苯基溴化膦

98%

同義詞:

(4-羟基-4-氧代丁基)三苯基溴化膦

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About This Item

線性公式:
HO2C(CH2)3P(C6H5)3Br
CAS號碼:
17857-14-6
分子量：:
429.29
MDL號碼:
MFCD00274196
分類程式碼代碼:
12352002
PubChem物質ID:
24861704
NACRES:
NA.22
暫時無法取得訂價和供貨情況

品質等級

100

化驗

98%

反應適用性

reaction type: C-C Bond Formation

mp

244-247 °C (lit.)

官能基

carboxylic acid
phosphine

SMILES 字串

[Br-].OC(=O)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

InChI

1S/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H

InChI 密鑰

NKVJKVMGJABKHV-UHFFFAOYSA-N

相關類別

應用

用作制备以下物质的反应物：
  • 哌啶类似物，作为具有抗肿瘤活性的组蛋白脱乙酰基酶（HDAC）抑制剂
  • 含硼的苯并氧杂硼烷类化合物，作为抗疟药
  • 甲基烯基喹诺酮类化合物，作为抗分枝杆菌剂
  • 依次经过Sharpless环氧化反应、Taber环丙烷化反应、化学选择性还原反应和锂化-硼化-烯丙基化反应，合成Solandelactone E
  • 有机锡化合物，作为抗真菌剂
  • 齐墩果酸衍生物作为蛋白酪氨酸磷酸酶1B的抑制剂，可抑制胰岛素途径（糖尿病和肥胖症治疗的有前景的靶标）
  • 11-oxa前列腺素类似物，具有降眼压活性

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H315,H319,H335

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number
STBJ7310
STBJ8668
STBF2050V
21706LH
14629KE

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