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Merck
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文件

229075

Sigma-Aldrich

1,8-Dihydroxy-3-methylanthraquinone

98%

同義詞:

3-Methylchrysazin, Chrysophanic acid

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About This Item

經驗公式(希爾表示法):
C15H10O4
CAS號碼:
分子量::
254.24
Beilstein:
1252300
EC號碼:
MDL號碼:
分類程式碼代碼:
51102829
PubChem物質ID:
NACRES:
NA.85

化驗

98%

形狀

crystalline

顏色

yellow-orange

溶解度

chloroform: 1%

抗生素活性譜

neoplastics
viruses

作用方式

enzyme | inhibits

SMILES 字串

Cc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1

InChI

1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3

InChI 密鑰

LQGUBLBATBMXHT-UHFFFAOYSA-N

基因資訊

human ... ELA2(1991)

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應用

Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells . It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro .

生化/生理作用

Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway . Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus .

其他說明

Keep container tightly closed in a dry and well-ventilated place.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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