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Merck
  • Molecular iodine-catalyzed facile procedure for N-Boc protection of amines.

Molecular iodine-catalyzed facile procedure for N-Boc protection of amines.

The Journal of organic chemistry (2006-10-10)
Ravi Varala, Sreelatha Nuvula, Srinivas R Adapa
摘要

An efficient and practical protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of a catalytic amount of molecular iodine (10 mol %) under solvent-free conditions at ambient temperature is presented.

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Sigma-Aldrich
1-Boc-哌嗪, 97%