推薦產品
化驗
95%
mp
226-229 °C (lit.)
SMILES 字串
[O-][N+](=O)c1ccc2C(=O)OC(=O)c3cccc1c23
InChI
1S/C12H5NO5/c14-11-7-3-1-2-6-9(13(16)17)5-4-8(10(6)7)12(15)18-11/h1-5H
InChI 密鑰
LKOZHLXUWUBRDK-UHFFFAOYSA-N
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一般說明
4-Nitro-1,8-naphthalic anhydride is a yellow crystalline nitrocompound widely used in the field of dye synthesis and cellular imaging.
應用
4-Nitro-1,8-naphthalic anhydride can be used:
- As a precursor to synthesize N-phenyl-amino-1,8-naphthalimide based fluorescent chemosensor to detect nitro-antibiotics at ppb level.[1]
- As a building block to synthesize shape memory polymers due to its ability to undergo Diels-Alder reaction
- As a fluorochrome substrate for nitrogen reductase for noninvasive hypoxia imaging in cancer detection.[2]
- As a precursor to synthesize amphiphilic naphthalimide dyes with good color brilliancy.[3]
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
Jin Zhou et al.
Chemistry, an Asian journal, 11(19), 2719-2724 (2016-02-09)
A lysosome-targeting fluorescent off-on probe has been developed by one-step synthesis for detecting lysosomal nitroreductase and hypoxia. The probe is constructed by incorporating morpholine (a lysosome-targeting unit) into 4-nitro-1,8-naphthalimide (as a fluorochrome and specific substrate for nitroreductase), and the detection
Desislava Staneva et al.
Sensors (Basel, Switzerland), 20(12) (2020-06-25)
In this study, a novel 6-(allylamino)-2-(2-(dimethylamino)ethyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione (NI3) was synthesized and characterized. Its copolymer with styrene was also obtained. The photophysical characteristics of NI3 were investigated in organic solvents and the results were compared with those of its structural analogue, 2-allyl-6-((2-(dimethylamino)ethyl)amino)-1H-benzo[de]isoquinoline-1,3(2H)-dione
Synthesis of disperse dyes derived from 4-amino-N-decyl-1, 8-naphthalimide and their dyeing properties on polyester fabrics
Umar Salami Ameuru, et al.
Dyes and Pigments, 157, 190-197 (2018)
Discriminative fluorescent sensing of nitro-antibiotics at ppb level using N-phenyl-amino-1,8-naphthalimides chemosensors
Ananthu Shanmughan, et al.
Results in Chemistry, 4, 100546-100546 (2022)
Naphthalimides in fluorescent imaging of tumor hypoxia ? An up-to-date review
Rashmi Kumari, et al.
Bioorganic Chemistry, 88, 102979-102979 (2019)
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