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重要文件

290890

Sigma-Aldrich

二醋酸二丁基锡

technical grade

同義詞:

二正丁基二乙酸锡

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About This Item

線性公式:
(CH3CH2CH2CH2)2Sn(OCOCH3)2
CAS號碼:
分子量::
351.03
Beilstein:
4136035
EC號碼:
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:
NACRES:
NA.22
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等級

technical grade

品質等級

蒸汽密度

12 (vs air)

蒸汽壓力

1.3 mmHg ( 25 °C)

折射率

n20/D 1.471 (lit.)

bp

142-145 °C/10 mmHg (lit.)

mp

7-10 °C (lit.)

密度

1.32 g/mL at 25 °C (lit.)

SMILES 字串

CCCC[Sn](CCCC)(OC(C)=O)OC(C)=O

InChI

1S/2C4H9.2C2H4O2.Sn/c2*1-3-4-2;2*1-2(3)4;/h2*1,3-4H2,2H3;2*1H3,(H,3,4);/q;;;;+2/p-2

InChI 密鑰

JJLKTTCRRLHVGL-UHFFFAOYSA-L

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一般說明

二乙酸二丁基锡是一种有机锡化合物,常用作有机合成中的催化剂[1][2]

應用

二乙酸二丁基锡可用作合成以下物质的催化剂:
  • 在三甲基甲硅基叠氮化物存在的情况下与各种腈反应制备Wittenberger四唑衍生物[1]
  • 在二氯甲烷溶剂存在的情况下以各种异氰酸酯和醇反应制备氨基甲酸酯衍生物[2]
  • 在4-甲基吗啉存在的情况下以芳基异氰酸酯和各种胺制备脲衍生物 [3]

訊號詞

Danger

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Muta. 2 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 - STOT SE 1 Oral

標靶器官

thymus gland, thymus gland,Immune system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

302.9 °F - Pensky-Martens closed cup

閃點(°C)

150.5 °C - Pensky-Martens closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Adrian Blaser et al.
Journal of medicinal chemistry, 55(1), 312-326 (2011-12-14)
Analogues of clinical tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824), in which the OCH(2) linkage was replaced with amide, carbamate, and urea functionality, were investigated as an alternative approach to address oxidative metabolism, reduce lipophilicity, and improve aqueous solubility. Several soluble monoaryl examples
TMSN3-Bu2Sn (OAc) 2: A modified and mild reagent system for Wittenberger tetrazole-synthesis
Yoneyama H, et al.
Tetrahedron Letters, 61, 151517-151517 (2020)
Wenhua Chu et al.
Bioorganic & medicinal chemistry, 17(3), 1222-1231 (2009-01-03)
A series of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs were synthesized. Among them, WC-26 and WC-59 were identified as the most potent sigma(2) receptor ligands (K(i)=2.58 and 0.82 nM, respectively) with high selectivity against sigma(1) (K(i) of sigma(1)/sigma(2) ratio=557 and 2087, respectively).
Critical gestational day of teratogenesis by di-n-butyltin diacetate in rats.
T Noda et al.
Bulletin of environmental contamination and toxicology, 49(5), 715-722 (1992-11-01)
B B Harsanyi et al.
Journal of dental research, 70(6), 991-996 (1991-06-01)
The hamster cheek pouch provides a suitable model system for the mucous-membrane irritation testing of dental materials. Poor retention of materials or difficulties in histopathological interpretation caused by surgical artifacts have been reported in published techniques. We describe a new

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