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Merck
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文件

242632

Sigma-Aldrich

2-氯乙基甲基硫醚

97%

同義詞:

2-(甲硫基)氯乙烷, Hemisulfur mustard

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About This Item

線性公式:
ClCH2CH2SCH3
CAS號碼:
分子量::
110.61
Beilstein:
1731033
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

形狀

liquid

折射率

n20/D 1.496 (lit.)

bp

55-56 °C/30 mmHg (lit.)

密度

1.11 g/mL at 25 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

CSCCCl

InChI

1S/C3H7ClS/c1-5-3-2-4/h2-3H2,1H3

InChI 密鑰

MYFKLQFBFSHBPA-UHFFFAOYSA-N

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應用

2-Chloroethyl methyl sulfide is a monofunctional chemical analog of sulfur mustard and has been used to study the potential of 2,6-dithiopurine as an antagonist of sulfur mustard.

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Carc. 1A - Flam. Liq. 3 - Skin Corr. 1B

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

107.6 °F - closed cup

閃點(°C)

42 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


分析證明 (COA)

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J R King et al.
Toxicology and applied pharmacology, 104(1), 167-179 (1990-06-01)
Previous research has shown the isolated perfused porcine skin flap (IPPSF) to be a novel in vitro experimental model for investigating xenobiotic percutaneous absorption. In this study, the IPPSF was used to biochemically and morphologically assess the dermatotoxicity of 2-chloroethyl
Y W Sohn et al.
Carcinogenesis, 17(6), 1361-1364 (1996-06-01)
Vinthionine (S-vinyl-DL-homocysteine) is hepatocarcinogenic in rats and mice. [Vinyl-14C]vinthionine binds covalently to rat liver DNA, RNA and protein in vivo, but not in vitro. This amino acid is directly mutagenic in Salmonella typhimurium TA100 and TA1535; the mechanism of its
Bruna Scaggiante et al.
Hematological oncology, 31(2), 110-116 (2012-08-30)
The elongation factor 1A proteins (eEF1A1/A2) are known to play a role in tumours. We previously found that a more basic isoform of eEF1A (MBI-eEF1A) is present in the cytoskeletal/nuclear-enriched extracts of CCRF-CEM T-lymphoblasts but not in those of normal
G R Klinefelter et al.
Journal of andrology, 18(2), 139-150 (1997-03-01)
In a previous study, we found that ethane dimethanesulphonate (EDS) compromised the fertilizing ability of proximal cauda epididymal sperm from the rat within 4 days of exposure, an effect that persisted in castrated, testosterone (T)-implanted animals, establishing direct action on
K Leslie Powell et al.
Chemical research in toxicology, 23(3), 497-503 (2010-01-07)
Sulfur mustard (bis-(2-chloroethyl)sulfide) is a well-known chemical warfare agent that induces debilitating cutaneous toxicity in exposed individuals. It is also known to be carcinogenic and mutagenic because of its ability to damage DNA via electrophilic attack. We previously showed that

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