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重要文件

232270

Sigma-Aldrich

3-氨基-5-甲基异噁唑

≥97%

同義詞:

5-甲基-3-异恶唑胺, NSC 159134

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About This Item

經驗公式(希爾表示法):
C4H6N2O
CAS號碼:
分子量::
98.10
Beilstein:
108110
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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化驗

≥97%

形狀

solid

mp

59-61 °C (lit.)

SMILES 字串

Cc1cc(N)no1

InChI

1S/C4H6N2O/c1-3-2-4(5)6-7-3/h2H,1H3,(H2,5,6)

InChI 密鑰

FKPXGNGUVSHWQQ-UHFFFAOYSA-N

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一般說明

3-氨基-5-甲基异恶唑是 嗜冷假单胞菌 菌株 HA-4 [1] 在磺胺甲恶唑生物降解过程中形成的主要中间体。它是磺胺甲恶唑 (SMX) 光催化降解过程中形成的中间体 [2]

應用

3-氨基-5-甲基异恶唑用于合成:
  • 萘并[1,2-e][1,3]恶嗪[3]
  • 1-芳基-4-甲基-3,6--(5-甲基异恶唑-3-基)-2-硫代-2,3,6,10 b -四氢-1 H -嘧啶并[5,4- c ] ] 喹啉-5-酮系列,具有潜在的杀蚊杀幼活性[4]
  • 磺胺嘧啶和硫胺甲恶唑的羟胺[5]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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An expeditious, straightforward and efficient synthesis of diversely naphtho[1,2-e][1,3]oxazines via one-pot condensation reaction of β- naphthol, 3-amino-5-methylisoxazole and arylaldehydes catalyzed by bismuth(III) trifluoromethanesulfonate is described. The reaction preferentially afforded 1,3-trans oxazines.
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Journal of hazardous materials, 262, 812-818 (2013-10-22)
Photocatalytic degradation of sulfamethoxazole (SMX) was investigated using Bi2O3/Bi2O2CO3/Sr6Bi2O9 (BSO) photocatalyst under visible light (>420 nm) irradiation. The photochemical degradation of SMX followed pseudo-first-order kinetics. The reaction kinetics was determined as a function of initial SMX concentrations (5-20 mg L(-1))
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Sulfamethoxazole is a common antibiotic that is frequently detected in wastewater and surface water. This study investigated the biodegradation and metabolic pathway of sulfamethoxazole by Pseudomonas psychrophila HA-4, a cold-adapted bacterium. Strain HA-4, which uses sulfamethoxazole as its sole source
Lu Wang et al.
Water research, 88, 322-328 (2015-10-30)
Sulphamethoxazole (SMX) is extensively used in humans and livestock, but its appearance in natural water raises environmental concerns. This study demonstrated that SMX and its degradation product, 3-amino-5-methylisoxazole (3A5MI), could be effectively degraded in microbial fuel cell (MFC) reactors. Approximately
Yan Li et al.
The Science of the total environment, 633, 1217-1226 (2018-05-16)
Sulfamethoxazole (SMX) is a sulfonamide antibiotic, widely used as curative and preventive drug for human, animal, and aquaculture bacterial infections. Its residues have been ubiquitously detected in the surface waters and sediments. In the present study, SMX dissipation and kinetics

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