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重要文件

196657

Sigma-Aldrich

1-氟萘

99%

同義詞:

α-氟萘

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About This Item

經驗公式(希爾表示法):
C10H7F
CAS號碼:
分子量::
146.16
Beilstein:
1906413
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

99%

形狀

liquid

折射率

n20/D 1.593 (lit.)

bp

215 °C (lit.)

mp

−13 °C (lit.)

密度

1.1322 g/mL at 20 °C (lit.)

官能基

fluoro

SMILES 字串

Fc1cccc2ccccc12

InChI

1S/C10H7F/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7H

InChI 密鑰

CWLKTJOTWITYSI-UHFFFAOYSA-N

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一般說明

研究了 O 2 和 1-氟萘混合物在气相中的闪光光解反应 [1]

應用

1-氟萘用于 t -BuLi 介导的 6-取代菲啶的合成 [2]。它也被用于合成 LY248686,一种 5-羟色胺和去甲肾上腺素摄取的强效抑制剂 [3]

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

149.0 °F - closed cup

閃點(°C)

65 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Slide 1 of 1

1 of 1

Asymmetric synthesis and absolute stereochemistry of LY248686.
Deeter J, et al.
Tetrahedron Letters, 31(49), 7101-7104 (1990)
Formation of O 2 (1Sigma g+) by 1-fluoronaphthalene sensitization.
Andrews LJ and Abrahamson EW.
Chemical Physics Letters, 10, 113-116 (1971)
Jan Pawlas et al.
Organic letters, 4(16), 2687-2690 (2002-08-03)
[reaction: see text] A one-pot, t-BuLi-induced synthesis of 6-substituted phenanthridines from fluoroarenes and nitriles via 1,2-arynes is reported. Aryl- and hetaryl nitriles, cyanamides, and trimethylacetonitrile gave phenanthridine products. The method was extended to provide bisphenanthridine 10 by a one-pot bis-cyclization
Peter Wipf et al.
Organic letters, 5(7), 1155-1158 (2003-03-28)
[reaction: see text] Electron-rich dinaphthyl ethers were synthesized by S(N)Ar reactions between naphthols and activated fluoronaphthalenes. 2-tert-Butyl-1,1,3,3-tetramethylguanidine (Barton's base) was found to be an excellent, mild alternative to traditional inorganic bases for promoting the coupling reaction.
C E Cerniglia et al.
Applied and environmental microbiology, 48(2), 294-300 (1984-08-01)
The metabolism of 1-fluoronaphthalene by Cunninghamella elegans ATCC 36112 was studied. The metabolites were isolated by reverse-phase high-pressure liquid chromatography and characterized by the application of UV absorption, 1H nuclear magnetic resonance, and mass spectral techniques. C. elegans oxidized 1-fluoronaphthalene

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