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131377

Sigma-Aldrich

1,10-菲啰啉

≥99%

同義詞:

o-phenanthroline

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About This Item

經驗公式(希爾表示法):
C12H8N2
CAS號碼:
分子量::
180.21
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
eCl@ss:
39210124
PubChem物質ID:
NACRES:
NA.22
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品質等級

化驗

≥99%

形狀

powder

mp

114-117 °C (lit.)

SMILES 字串

c1cnc2c(c1)ccc3cccnc23

InChI

1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H

InChI 密鑰

DGEZNRSVGBDHLK-UHFFFAOYSA-N

基因資訊

human ... FNTA(2339)

應用

1,10-菲咯啉可用作:
  • 阴极缓冲层,以提高有机太阳能电池的效率。[1]
  • 常规螯合剂,用于研究其在Fenton反应-鲁米诺化学发光系统中的功效。[2]
  • 温和的铜(II)催化有机硼酸和亚磺酸盐的交叉偶联的配体,从而形成芳基和烯基砜。[3]
  • 一种用于金属[4]分光光测定和二氧化碳光催化还原的通用配体。[5]
  • 金属大环化合物合成砌块。[6]

象形圖

Skull and crossbonesEnvironment

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


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分析證明 (COA)

Lot/Batch Number

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Mitsuhiro Wada et al.
Luminescence : the journal of biological and chemical luminescence, 29(7), 955-958 (2014-01-10)
In vitro screening of a Fe(2+) -chelating effect using a Fenton's reaction-luminol chemiluminescence (CL) system is described. The luminescence between the reactive oxygen species generated by the Fenton's reaction and luminol was decreased on capturing Fe(2+) using a chelator. The
Catalysis by Metal Complexes, 14, 217-217 (1993)
Neville S Ng et al.
Dalton transactions (Cambridge, England : 2003), 42(9), 3196-3209 (2012-12-13)
Copper(II) (1(Cu)-21(Cu)) and previously established experimental anticancer platinum(II) metallointercalator complexes (1(Pt)-16(Pt)) have been prepared and investigated for their antimicrobial properties. These complexes are of the general structure [M(I(L))(A(L))](2+) where I(L) represents functionalised 1,10-phenanthrolines (1(IL)-10(IL)), and A(L) represents 1,2-diaminoethane, 1S,2S- or
Aswan Sci. Technol. Bull., 13, 3-3 (1992)
Daisuke Nishimiya et al.
Scientific reports, 9(1), 11436-11436 (2019-08-09)
Proteases are one of attractive therapeutic targets to play key roles in pharmacological action. There are many protease inhibitors in nature, and most of them structurally have cystine knot motifs. Their structures are favorable for recognition of active pockets of

Questions

1–7 of 7 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Do you have GMP pharmaceutical grade 1,10-Phenanthroline?

    1 answer
    1. Unfortunately, there are no GMP or pharmaceutical grade products available at this time.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. What is the difference between 1,10-Phenanthroline Products 131377 and 320056?

    1 answer
    1. Product 320056 is the monohydrate form and 131377 has no specification on water content. Both can make a copper complex, since they are the same ligand.

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  6. Can Product 131377, 1,10-Phenanthroline, be used for cell culture?

    1 answer
    1. Sigma-Aldrich does not have any references for the use of 1,10-phenanthroline in cell culture.

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  7. What is the solubility of Product 131377, 1,10-Phenanthroline?

    1 answer
    1. 1,10-Phenanthroline is soluble in methanol at 500 micrograms per mL, or in water at 3 milligrams per mL. It is also soluble in benzene and acetone.

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