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Merck
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重要文件

109509

Sigma-Aldrich

2-氯苯肼 盐酸盐

97%

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About This Item

線性公式:
ClC6H4NHNH2·HCl
CAS號碼:
分子量::
179.05
Beilstein:
3699381
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
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化驗

97%

mp

200-203 °C (dec.) (lit.)

SMILES 字串

Cl.NNc1ccccc1Cl

InChI

1S/C6H7ClN2.ClH/c7-5-3-1-2-4-6(5)9-8;/h1-4,9H,8H2;1H

InChI 密鑰

ADODRSVGNHNKAT-UHFFFAOYSA-N

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應用

2-Chlorophenylhydrazine hydrochloride was used to study intrinsic resistance of Mycobacterium smegmatis to fluoroquinolones, used for treatment of Mycobacterium tuberculosis[1]. It may be used in pyrazoline synthesis[2].

象形圖

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訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Mohammad Abdel-Halim et al.
Bioorganic & medicinal chemistry, 21(23), 7343-7356 (2013-10-22)
Derivatives with scaffolds of 1,3,5-tri-substituted pyrazoline and 1,3,4,5-tetra-substituted pyrazoline were synthesized and tested for their inhibitory effects versus the p53(+/+) HCT116 and p53(-/-) H1299 human tumor cell lines. Several compounds were active against the two cell lines displaying IC50 values
C Montero et al.
Antimicrobial agents and chemotherapy, 45(12), 3387-3392 (2001-11-16)
The fluoroquinolones (FQ) are used in the treatment of Mycobacterium tuberculosis, but the development of resistance could limit their effectiveness. FQ resistance (FQ(R)) is a multistep process involving alterations in the type II topoisomerases and perhaps in the regulation of

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