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重要文件

G2417

Supelco

甲磺酸加贝酯

analytical standard, for drug analysis

同義詞:

4-(6-胍基己酰氧基)苯甲酸乙酯甲磺酸盐, 4-[[6-[(氨基亚氨基甲基)氨基]-1-氧己基]氧]苯甲酸乙酯 甲磺酸盐, 福耶

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About This Item

經驗公式(希爾表示法):
C16H23N3O4 · CH4O3S
CAS號碼:
分子量::
417.48
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.24

等級

analytical standard, for drug analysis

品質等級

形狀

solid

技術

HPLC: suitable
gas chromatography (GC): suitable

應用

forensics and toxicology
pharmaceutical (small molecule)
veterinary

形式

neat

SMILES 字串

CS(O)(=O)=O.CCOC(=O)c1ccc(OC(=O)CCCCCNC(N)=N)cc1

InChI

1S/C16H23N3O4.CH4O3S/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18;1-5(2,3)4/h7-10H,2-6,11H2,1H3,(H4,17,18,19);1H3,(H,2,3,4)

InChI 密鑰

DNTNDFLIKUKKOC-UHFFFAOYSA-N

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一般說明

Gabexate mesylate is a non-antigenic synthetic inhibitor of trypsin-like serine proteinases, which finds therapeutic applications in the treatment of disseminated intravascular coagulation and pancreatitis. It also plays the role of an anticoagulant in hemodialysis therapy.

應用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Tomoki Nishiyama et al.
The American journal of emergency medicine, 30(7), 1219-1223 (2011-12-30)
We hypothesized that antithrombin is more effective for disseminated intravascular coagulation (DIC) than is gabexate mesilate, which is a protease inhibitor, suggested from the previous studies. Initially, we compared the effects of antithrombin and gabexate mesilate for treating infection-related DIC.
S Aosasa et al.
Shock (Augusta, Ga.), 15(2), 101-105 (2001-02-28)
If the inflammatory response becomes excessive or uncontrolled by some stimuli, inappropriate inflammatory responses occur. Monocytes are extremely important cells for regulating the cytokine network and tumor necrosis factor alpha (TNFalpha) and interleukin- (IL) 10, which are mainly synthesized by
Maria Dorly Del Curto et al.
Journal of pharmaceutical sciences, 100(8), 3251-3259 (2011-04-06)
It is well known that the intestinal stability and absorption of protein drugs are improved when enzyme inhibitors/permeation enhancers are coadministered. Recently, it was hypothesized that an increased effectiveness of these adjuvants might be achieved by timing their release prior
Kohei Uchimura et al.
American journal of physiology. Renal physiology, 303(7), F939-F943 (2012-07-27)
Aldosterone plays an important role in the regulation of blood pressure by modulating the activity of the epithelial sodium channel (ENaC) that consists of α-, β-, and γ-subunits. Aldosterone induces a molecular weight shift of γENaC from 85 to 70
James A Reihill et al.
Biomolecules, 10(4) (2020-04-02)
Epithelial barrier dysfunction, characteristic of allergic airway disease may be, at least in part, due to the action of allergen-associated protease activities. Cockroach allergy is a major global health issue, with cockroaches containing considerable serine trypsin-like protease (TLP) activity. The

文章

Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.

分析酵素 Chymotrypsin:糜蛋白酶在胰腺的胰腺尖細胞中以非活性前體糜蛋白酶原的形式產生。

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