1247003

Erythromycin lactobionate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Erythromycin 4-O-β-D-galactopyranosyl-D-gluconate
• Empirical Formula (Hill Notation): C₃₇H₆₇NO₁₃ · C₁₂H₂₂O₁₂
• CAS Number: 3847-29-8
• Molecular Weight: 1092.22
• MDL number: MFCD29917802
• UNSPSC Code: 41116107
• EC Number: 223-348-7
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• agency: USP
• API family: erythromycin
• form: powder
• manufacturer/tradename: USP
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat
• SMILES string: N([C@@H]2[C@H]([C@@H](O[C@@H](C2)C)O[C@@H]3[C@H]([C@@H]([C@H](C(=O)O[C@@H]([C@]([C@@H]([C@H](C(=O)[C@@H](C[C@]3(O)C)C)C)O)(O)C)CC)C)O[C@@H]4O[C@H]([C@@H]([C@@](C4)(OC)C)O)C)C)O)(C)C.O1[C@H]([C@@H]([C@H]([C@H]([C@H]1CO)O)O)O)O[C@@H]([C@H](O)[C@@H](O)C(=O)O
• InChI: 1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1
• InChI key: NNRXCKZMQLFUPL-WBMZRJHASA-N

Description

General description

Erythromycin lactobionate is a highly water-soluble form of erythromycin used primarily in intravenous preparations. It retains the macrolide′s mechanism of action, targeting the 50S ribosomal subunit. The USP reference standard supports analytical testing for intravenous dosage forms.

The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle.

The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Erythromycin lactobionate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Erythromycin Lactobionate for Injection
• Sterile Erythromycin Lactobionate

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of the USP Biologics program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable