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Pro-Gly

Name: Pro-Gly
Brand: SIGMA

≥98% (TLC), suitable for cell culture

Synonym(s):

L-prolyl-glycine

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About This Item

Empirical Formula (Hill Notation):

C₇H₁₂N₂O₃

CAS Number:

2578-57-6

Molecular Weight:

172.18

UNSPSC Code:

12352202

PubChem Substance ID:

24898135

NACRES:

NA.26

MDL number:

MFCD00022391

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Properties

Product Name

Pro-Gly,

assay

≥98% (TLC)

Quality Level

200

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

application(s)

cell analysis

storage temp.

−20°C

SMILES string

OC(=O)CNC(=O)[C@@H]1CCCN1

InChI

1S/C7H12N2O3/c10-6(11)4-9-7(12)5-2-1-3-8-5/h5,8H,1-4H2,(H,9,12)(H,10,11)/t5-/m0/s1

InChI key

RNKSNIBMTUYWSH-YFKPBYRVSA-N

Description

Biochem/physiol Actions

PRO-GLY is a dipeptide that has previously been shown to prevent progression of diabetes.

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This Item	G3915	M4139	A0878
Sigma-Aldrich P0880 Pro-Gly	Sigma-Aldrich G3915 Gly-Gly	Sigma-Aldrich M4139 S-Methylglutathione	Sigma-Aldrich A0878 Ala-Gly
form powder	form powder	form powder	form powder
assay ≥98% (TLC)	assay ≥99%	assay >98% (TLC)	assay ≥99% (TLC)
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) -
storage temp. −20°C	storage temp. -	storage temp. 2-8°C	storage temp. −20°C
Quality Level 200	Quality Level 400	Quality Level 200	Quality Level 200
color white	color white	color white	color white

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Dissecting the proline effect: dissociations of proline radicals formed by electron transfer to protonated Pro-Gly and Gly-Pro dipeptides in the gas phase.

Shigeo Hayakawa et al.

Journal of the American Chemical Society, 129(25), 7936-7949 (2007-06-07)

We report a combined experimental and computational study of the proline effect in model dipeptides Pro-Gly and Gly-Pro. Gas-phase protonated peptide ions were discharged by glancing collisions with potassium or cesium atoms at 3 keV collision energies, and the peptide

N-primary-amine-terminal beta-turn tetrapeptides as organocatalysts for highly enantioselective aldol reaction.

Feng-Chun Wu et al.

The Journal of organic chemistry, 74(13), 4812-4818 (2009-05-23)

Tetrapeptides, containing a terminated primary amine and conformationally restricted D-Pro-Gly or D-Pro-Aib (2-aminoisobutanoic acid) segment as a strongly beta-turn-nucleating element, were designed and synthesized with condensation of N-module dipeptides with C-module dipeptides in solution. They were first applied to catalyze

The di- and tripeptide transport protein of Lactococcus lactis. A new type of bacterial peptide transporter.

A Hagting et al.

The Journal of biological chemistry, 269(15), 11391-11399 (1994-04-15)

Lactococcus lactis takes up di- and tripeptides via a proton motive force-dependent carrier protein. The gene (dtpT) encoding the di-tripeptide transport protein of L. lactis was cloned by complementation of a dipeptide transport-deficient and proline auxotrophic Escherichia coli strain. Functional