F2929
6-Fluoromevalonate
≥90% (GC), Mevalonate-pyrophosphate decarboxylase inhibitor, viscous liquid
Synonym(s):
Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one, ZR 3516
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About This Item
Product Name
6-Fluoromevalonate, ≥90% (GC), viscous liquid
Quality Level
assay
≥90% (GC)
form
viscous liquid
color
yellow tint
solubility
DMSO: ≥3 mg/mL
storage temp.
2-8°C
SMILES string
OC1(CF)CCOC(=O)C1
InChI
1S/C6H9FO3/c7-4-6(9)1-2-10-5(8)3-6/h9H,1-4H2
InChI key
DPPMVKMESJJAJZ-UHFFFAOYSA-N
Application
- to study the effect of mevalonate pathway inhibition on patient-derived brain tumor-initiating cells (BTICs) growth and self-renewal
- to study its effect on induction of trained immunity by β-glucan in monocytes
- to determine the effect of the mevalonate pathway (MVP) on ADP-ribosylation factor 6 (ARF6) activation
Biochem/physiol Actions
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥90% (GC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form viscous liquid | form powder | form solid | form powder |
| Quality Level 100 | Quality Level - | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: ≥3 mg/mL | solubility DMSO: 2 mg/mL, clear | solubility DMSO: >10 mg/mL, clear | solubility DMSO: 15 mg/mL, clear |
| color yellow tint | color white to beige | color off-white | color white to beige |
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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