E5264

2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine perchlorate

analytical standard, for drug analysis

• Empirical Formula (Hill Notation): C₂₀H₂₃N · HClO₄
• CAS Number: 66729-78-0
• Molecular Weight: 377.86
• UNSPSC Code: 41116107
• PubChem Substance ID: 329799066
• MDL number: MFCD00132956

Properties

• Quality Segment: 200
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: OCl(=O)(=O)=O.C\C=C1/N(C)C(C)CC1(c2ccccc2)c3ccccc3
• InChI: 1S/C20H23N.ClHO4/c1-4-19-20(15-16(2)21(19)3,17-11-7-5-8-12-17)18-13-9-6-10-14-18;2-1(3,4)5/h4-14,16H,15H2,1-3H3;(H,2,3,4,5)/b19-4-;
• InChI key: CBNJWAYHGKHAFJ-YOJQKEKBSA-N

Description

General description

2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine perchlorate is a primary metabolite of methadone.

Application

A metabolite of methadone, useful as a marker in GC-MS analyses.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

2-Ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine perchlorate has been used as a standard in the quantitative determination of of methadone and metabolites in human meconium using liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry technique (LC–APCI–MS/MS).

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)