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E1283

ERK2, active, GST tagged human

recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

ERT1, MAPK1, MAPK2, P41mapk, P42MAPK, PRKM1, PRKM2, p40, p47

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About This Item

NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
613-829 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in E. coli
Pricing and availability is not currently available.
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recombinant

expressed in E. coli

Quality Level

200

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

613-829 nmol/min·mg

mol wt

~68 kDa

UniProt accession no.

P28482

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... MAPK1(5594)

Biochem/physiol Actions

ERK2 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs) which are activated in response to numerous growth factors and cytokines. Activation of ERK2 requires both tyrosine and threonine phosphorylation that is mediated by MEK. ERK2 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK2 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta).

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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This Item
SAB5700003SAB5700045SRP5242
ERK2, active, GST tagged human recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

E1283

ERK2, active, GST tagged human

Anti-ERK2 antibody produced in rabbit

Sigma-Aldrich

SAB5700003

Anti-ERK2 antibody produced in rabbit

Anti-ERK2 antibody produced in rabbit

Sigma-Aldrich

SAB5700045

Anti-ERK2 antibody produced in rabbit

ERK5, active, GST tagged human PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sigma-Aldrich

SRP5242

ERK5, active, GST tagged human

specific activity

613-829 nmol/min·mg

specific activity

-

specific activity

-

specific activity

9.4-12.7 nmol/min·mg

Gene Information

human ... MAPK1(5594)

Gene Information

human ... MAPK1(5594)

Gene Information

human ... MAPK1(5594)

Gene Information

human ... MAPK7(5598)

assay

≥70% (SDS-PAGE)

assay

-

assay

-

assay

≥70% (SDS-PAGE)

recombinant

expressed in E. coli

recombinant

-

recombinant

-

recombinant

expressed in baculovirus infected Sf9 cells

form

buffered aqueous glycerol solution

form

buffered aqueous solution

form

buffered aqueous solution

form

buffered aqueous glycerol solution

storage temp.

−70°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−70°C

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SLCH6189
SLCC0155
SLBL1213V
SLBJ1183V
SLBG4152

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T G Boulton et al.
Biochemistry, 30(1), 278-286 (1991-01-08)
In rat 1 fibroblasts, insulin has little or no stimulatory effect on the activities of either MAP2 protein kinase or ribosomal protein S6 kinase. In contrast, in rat 1 cells that overexpress the normal human insulin receptor (rat 1 HIRc

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