E0502

Elastin–Congo red

Name: Elastin–Congo red
Brand: SIGMA

elastase substrate

Synonym(s):

Elastin Congo red

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About This Item

UNSPSC Code:

12352204

NACRES:

NA.32

MDL number:

MFCD00131000

Key Documents

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form

powder

storage temp.

2-8°C

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This Item	C6277	C6767	234610
Sigma-Aldrich E0502 Elastin–Congo red	C6277 Congo Red	C6767 Congo Red	Sigma-Aldrich 234610 Congo Red, High Purity
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
form powder	form powder	form powder	form crystalline solid
storage temp. 2-8°C	storage temp. room temp	storage temp. room temp	storage temp. 15-25°C

General description

Substrate for the estimation of elastase.

Elastin−Congo red is a substrate-dye conjugate and is used in agar medium to probe elastase activity. The presence of elastase functionality leads to cleavage of the dye from the elastin substrate.

Application

Elastin−Congo red has been used as a substrate for neutrophil elastase, salivary elastase and P. aeruginosa.

Other Notes

Elastin impregnated with Congo red dye.

pictograms

GHS08

signalword

Danger

hcodes

H350,H361d

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 1B - Repr. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

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Development of an agar diffusion method to measure elastase inhibition activity using Elastin-Congo red

Jung KH and Kim HJ

Journal of microbiology and biotechnology, 16(8), 1320-1324 (2006)

Salivary immunity in elderly individuals presented with Candida-related denture stomatitis

Gasparoto T, et al.

Gerodontology, 29(2), e331-e339 (2012)

Coumarin Exhibits Broad-Spectrum Antibiofilm and Antiquorum Sensing Activity against Gram-Negative Bacteria: In Vitro and In Silico Investigation.

Faizan Abul Qais et al.

ACS omega, 6(29), 18823-18835 (2021-08-03)

Quorum sensing (QS) and biofilm inhibition are recognized as the novel drug targets for the broad-spectrum anti-infective strategy to combat the infections caused by drug-resistant bacterial pathogens. Many compounds from medicinal plants have been found to demonstrate anti-infective activity. However

AiiM lactonase strongly reduces quorum sensing controlled virulence factors in clinical strains of Pseudomonas aeruginosa isolated from burned patients

Lopez-Jacome LE, et al.

Frontiers in Microbiology, 10, 2657-2657 (2019)

Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis

Gasparoto TH, et al.

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 31(6), 1271-1277 (2012)

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การทำงานและความสำคัญของ Elastase

ดัชนีการประยุกต์ใช้อีลาสเทสเพื่อทำความเข้าใจเกี่ยวกับ leukocyte elastase ซึ่งเป็น endprotease serine 29 KDA

Elastase Function and Importance

Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.

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