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Dextran from Leuconostoc mesenteroides

Name: Dextran from <I>Leuconostoc mesenteroides</I>
Brand: SIGMA

average mol wt 150,000

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About This Item

Linear Formula:

(C₆H₁₀O₅)_n

CAS Number:

9004-54-0

UNSPSC Code:

12352201

NACRES:

NA.25

EC Number:

232-677-5

MDL number:

MFCD00130935

Pricing and availability is not currently available.

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Properties

biological source

bacterial (Leuconostoc mesenteroides)

Quality Segment

200

form

powder

optical activity

[α]/D 199°

mol wt

average mol wt 150,000

color

white

solubility

H₂O: soluble 20 mg/mL

SMILES string

O1C(C(C(C(C1CO)O)O)O)OCC2OC(C(C(C2O)O)O)OCC(O)C(O)C(O)C(O)C=O

InChI

1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2

InChI key

FZWBNHMXJMCXLU-UHFFFAOYSA-N

Description

Application

Dextrans are used in many applications as platelet aggregants, plasma volume extenders, osmotic pressure regulators, stabilizers, organ separation media, matrix components, copolymers, microcarriers, binding agents, viscosity modifiers, antithrombotics, lubricants and physical structure components.[1] Dextrans may be used as long hydrophilic spacer arms to improve the performance (freedom of movement) of conjugated/bound proteins. Dextrans may be derivatized for use in biosensor systems.[2] Dextran 150 may be used to study iron delivery to cells, cell membrane permeabilization and red blood cell aggregation.

Use of dextrans as long and hydrophilic spacer arms improves the performance of immobilized proteins acting on macromolecules.

Preparation Note

With the exception of the highest MW dextran, D5501 (MW range = 5 million to 40 million), dextrans are very water soluble. Sigma tests the solubility of dextrans at concentrations generally exceeding 30 mg/ml in water. Dextrans are also freely soluble in DMSO, formamide, ethylene glycol, and glycerol. Neutral-aqueous dextran solutions can be sterilized by autoclaving at 110-115^oC for 30 to 45 minutes. Dextran can be hydrolyzed by strong acids at high temperatures. The terminal reducing end group of dextran can be oxidized in alkaline solutions.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

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This Item	D3759	D8821	D1662
Sigma-Aldrich D4876 Dextran from Leuconostoc mesenteroides	Sigma-Aldrich D3759 Dextran from Leuconostoc mesenteroides	Sigma-Aldrich D8821 Dextran from Leuconostoc mesenteroides	Sigma-Aldrich D1662 Dextran from Leuconostoc mesenteroides
biological source bacterial (Leuconostoc mesenteroides)	biological source bacterial (Leuconostoc mesenteroides)	biological source bacterial (Leuconostoc mesenteroides)	biological source bacterial (Leuconostoc mesenteroides)
solubility H₂O: soluble 20 mg/mL	solubility H₂O: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow	solubility water: 100 mg/mL at 25 °C, colorless to faintly yellow	solubility H₂O: 100 mg/mL, clear, colorless
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
form powder	form powder	form powder	form powder
color white	color white	color white to off-white	color white
mol wt average mol wt 150,000	mol wt average mol wt 48,000-90,000	mol wt average mol wt 60,000-76,000	mol wt average mol wt 35,000-45,000