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D4266

3-(Decyldimethylammonio)­propane­sulfonate inner salt

zwitterionic detergent

Synonym(s):

Caprylyl sulfobetaine, SB3-10

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About This Item

Linear Formula:
CH3(CH2)9N+(CH3)2CH2CH2CH2SO3-
CAS Number:
Molecular Weight:
307.49
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3967284
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Quality Segment

assay

≥98.0% (TLC)

form

powder

mol wt

micellar avg mol wt 12,600

aggregation number

41

technique(s)

enzyme immunoassay: suitable, protein purification: suitable, protein quantification: suitable

conductivity

<20 μmho per cm at 24 °C (0.1 M aqueous solution)

CMC

25-40 mM (20-25°C)

SMILES string

CCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C15H33NO3S/c1-4-5-6-7-8-9-10-11-13-16(2,3)14-12-15-20(17,18)19/h4-15H2,1-3H3

InChI key

WKALLSVICJPZTM-UHFFFAOYSA-N

General description

3-(Decyldimethylammonio)­propane­sulfonate inner salt, a zwitterionic surfactant, is a sulfobetaine. Sulfobetaines contain a positively charged quaternary ammonium group and a negatively charged sulfonic group.

Application

Zwitterionic detergent used for protein solubilization.
3-(Decyldimethylammonio)­propane­sulfonate inner salt was used:
  • In a study to demonstrate a polyurethane chip that electrostatically binds to immunoglobulin G (IgG).[1]
  • In a study to describe a method for isolating a high yield of Arabidopsis chloroplasts.[2]
  • Solubilization of oleosins.

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Show Differences

1 of 1

This Item
D043140772H6883
assay

≥98.0% (TLC)

assay

>99% (TLC)

assay

≥98.0% (TLC)

assay

≥98% (TLC)

technique(s)

enzyme immunoassay: suitable, protein quantification: suitable, protein purification: suitable

technique(s)

-

technique(s)

nucleic acid detection: suitable, protein purification: suitable, protein quantification: suitable

technique(s)

electrophoresis: suitable, mass spectrometry (MS): suitable, thin layer chromatography (TLC): suitable

form

powder

form

powder

form

powder

form

-

aggregation number

41

aggregation number

55

aggregation number

83

aggregation number

155

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

CMC

25-40 mM (20-25°C)

CMC

2-4 mM (20-25°C)

CMC

0.1-0.4 mM (20-25°C)

CMC

0.01-0.06 mM (20-25°C)


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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W Schulz et al.
Journal of steroid biochemistry, 32(4), 581-590 (1989-04-01)
11 beta-hydroxysteroid dehydrogenase (11-HSD, EC 1.1.1.146) from rat renal cortex microsomes was solubilized using several detergents, the most effective being Zwittergent 3-10 and Triton X-100. The activity ratio oxidation/reduction of the reversible reaction corticosterone in equilibrium 11-dehydrocoticosterone varied depending on
Kenji Murakami et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(13), 4816-4821 (2012-03-14)
General transcription factor TFIIH, previously described as a 10-subunit complex, is essential for transcription and DNA repair. An eleventh subunit now identified, termed Tfb6, exhibits 45% sequence similarity to human nuclear mRNA export factor 5. Tfb6 dissociates from TFIIH as
Sybille E Kubis et al.
Methods in molecular biology (Clifton, N.J.), 425, 171-186 (2008-03-29)
A major area of research in the postgenomic era has been the proteomic analysis of various subcellular and suborganellar compartments. The success of these studies is to a large extent dependent upon efficient protocols for the preparation of highly pure



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