Fluorescein isothiocyanate–dextran

Name: Fluorescein isothiocyanate–dextran
Brand: SIGMA

average mol wt 2,000,000

Synonym(s):

FITC–Dextran 2000, FITC–Dextran

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About This Item

CAS Number:

60842-46-8

UNSPSC Code:

12352201

NACRES:

NA.32

MDL number:

MFCD00131092

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Properties

biological source

synthetic

Quality Segment

100

conjugate

FITC conjugate

form

powder or crystals

mol wt

average mol wt 2,000,000

extent of labeling

0.001-0.020 mol FITC per mol glucose (substitution)

fluorescence

λ_ex 493 nm; λ_em 520 nm in 0.1 M Tris pH 8.0

application(s)

cell analysis

Description

Application

Dextran labeled with fluorescein isothiocyanate for possible use in perfusion studies in animals.

Fluorescein isothiocyanate–dextran (FITC–Dextran 2000) is use as a fluorescent probe to study the permeability of structures such as intercellular junctions involved in processes such as hearing and vascular permeability and the integrity of the blood brain barrier (BBB).

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This Item	69658	FD2000S	FD40
Sigma-Aldrich 52471 Fluorescein isothiocyanate–dextran	Sigma-Aldrich 69658 Fluorescein isothiocyanate–dextran	Sigma-Aldrich FD2000S Fluorescein isothiocyanate–dextran	Sigma-Aldrich FD40 Fluorescein isothiocyanate–dextran
biological source synthetic	biological source synthetic	biological source synthetic (organic)	biological source bacterial (Leuconostoc mesenteroides)
Quality Level 100	Quality Level 100	Quality Level 200	Quality Level 100
form powder or crystals	form powder or crystals	form powder	form powder
application(s) cell analysis	application(s) cell analysis	application(s) -	application(s) -
fluorescence λ_ex 493 nm; λ_em 520 nm in 0.1 M Tris pH 8.0	fluorescence λ_ex 493 nm; λ_em 520 nm±5 nm in 0.1 M Tris pH 8.0	fluorescence -	fluorescence -
extent of labeling 0.001-0.020 mol FITC per mol glucose (substitution)	extent of labeling 0.001-0.020 mol/mol FITC glucose	extent of labeling 0.003-0.020 mol FITC per mol glucose	extent of labeling 0.001-0.020 mol FITC per mol glucose