ABE480
Anti-Centrin-2 Antibody
serum, from rabbit
Synonym(s):
Centrin-2, Caltractin isoform 1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, IHC, IP, WB
Citations:
2
Pricing and availability is not currently available.
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse, rat
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CETN2(1069)
General description
Centrin-2 is also called Caltractin isoform 1. Centrin-2 is involved in microtubule organization, structure and function, and is required for centriole duplication and spindle formation. Centrin-2 also has a role in regulating cytokinesis, genome stability and global genome nucleotide excision repair (GG-NER) as component of the XPC complex.
~18 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
Immunogen
Recombinant protein corresponding to human Centrin-2.
Application
Anti-Centrin-2 Antibody is a highly specific rabbit polyclonal antibody, that targets Centrin & has been tested in western blotting, ICC, IHC & IP.
Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in MDCK cells (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in wild type and galectin-3 null mouse kidney tissues (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).
Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Centrin-2 in MDCK cell lysate (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in wild type and galectin-3 null mouse kidney tissues (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).
Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Centrin-2 in MDCK cell lysate (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).
Analysis Note
Evaluated by Western Blotting in Jurkat cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Centrin-2 in 10 µg of Jurkat cell lysate.
Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Centrin-2 in 10 µg of Jurkat cell lysate.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Renee A Lopez et al.
Bio-protocol, 7(21), e2599-e2599 (2017-11-05)
Male gametes (spermatozoids) are the only motile cells produced during the life cycle of land plants. While absent from flowering and most cone-bearing plants, motile cells are found in less derived taxa, including bryophytes (mosses, liverworts and hornworts), pteridophytes (lycophytes
Ting Zhang et al.
Nature communications, 13(1), 6907-6907 (2022-11-15)
Transcription replication collisions (TRCs) constitute a major intrinsic source of genome instability but conclusive evidence for a causal role of TRCs in tumor initiation is missing. We discover that lack of the H4K20-dimethyltransferase KMT5B (also known as SUV4-20H1) in muscle