1460703

奈韦拉平

United States Pharmacopeia (USP) Reference Standard

• 别名: 11-环丙基-5,11-二氢-4-甲基-6H-二吡啶基[3,2-b:2′,3′-e][1,4] 二氮杂- 6-酮
• 经验公式（希尔记法）: C₁₅H₁₄N₄O
• CAS号: 129618-40-2
• 分子量: 266.30
• MDL编号: MFCD00866928
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329750549
• NACRES: NA.24

属性

• 等级: pharmaceutical primary standard
• API类: nevirapine
• 制造商/商品名称: USP
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• SMILES字符串: CC1=CC=NC2=C1NC(C(C=CC=N3)=C3N2C4CC4)=O
• InChI: 1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)
• InChI key: NQDJXKOVJZTUJA-UHFFFAOYSA-N

说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Nevirapine anhydrous USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Nevirapine
• Nevirapine Extended-Release Tablets
• Nevirapine Oral Suspension
• Nevirapine Tablets

生化/生理作用

HIV-1 的 NNRTI（非核苷类逆转录酶抑制剂）

奈韦拉平是 HIV 逆转录酶（NNRTI）的变构非核苷抑制剂。奈韦拉平抑制野生型 RT 的 K_i 为 200 nM。

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

Sales restrictions may apply.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable