推荐产品
等級
pharmaceutical primary standard
API 家族
nevirapine
製造商／商標名
EDQM
應用
pharmaceutical (small molecule)
形式
neat
儲存溫度
2-8°C
SMILES 字串
CC1=CC=NC2=C1NC(C(C=CC=N3)=C3N2C4CC4)=O
InChI
1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)
InChI 密鑰
NQDJXKOVJZTUJA-UHFFFAOYSA-N
正在寻找类似产品? 访问 产品对比指南
一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Nevirapine for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化／生理作用
HIV-1 的 NNRTI（非核苷类逆转录酶抑制剂）
奈韦拉平是 HIV 逆转录酶（NNRTI）的变构非核苷抑制剂。奈韦拉平抑制野生型 RT 的 Ki 为 200 nM。
包裝
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他說明
Sales restrictions may apply.
相關產品
产品编号
说明
价格
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
J-J Parienti et al.
Medecine et maladies infectieuses, 40(9), 499-505 (2010-05-04)
Taking into account long-term adverse effects of antiretroviral treatment has become a major concern for physicians managing HIV infected patients. More specifically, cardiovascular risk is the fourth cause of death in this population. Nevirapine, when used in antiretroviral naive patients
Laveeza Bhatti et al.
Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002), 11(6), 369-373 (2012-08-30)
Nevirapine (NVP) was the first nonnucleoside reverse transcriptase inhibitor (NNRTI) approved by the US Food and Drug Administration (FDA) in 1996, for the treatment of HIV infection. Current treatment guidelines include NVP as a component of a recommended alternative NNRTI
[Prevention of mother-to-child transmission with single dose nevirapine and human immunodeficiency virus drug resistance].
Jian-feng Han et al.
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 29(7), 730-733 (2008-11-27)
Juan Carlos Lopez-Delgado et al.
Annals of transplantation, 17(1), 122-127 (2012-04-03)
Acute liver failure (ALF) due to antiretroviral treatment is a rare but a fatal complication in HIV-infected patients. Non-nucleoside retroviral transcriptase inhibitors are known to cause hepatotoxicity and exceptionally acute hepatic failure. We report a case of nevirapine-induced acute liver
Emily L Heil et al.
Expert opinion on pharmacotherapy, 12(17), 2713-2718 (2011-11-01)
Nevirapine (NVP) was the first non-nucleoside reverse transcriptase inhibitor (NNRTI) approved for the treatment of HIV infection and quickly became one of the most extensively used antiretrovirals (ARVs) worldwide. A new extended-formulation of the drug has now been FDA approved
Active Filters
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门
