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生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 51 kDa
种属反应性
human, rat, mouse
浓度
~1 mg/mL
技术
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... HTR2C(3358)
一般描述
5-HT-2C/HTR2C (5-hydroxytryptamine receptor 2C) receptor is a seven transmembrane domain protein. It is located on human chromosome Xq22-23.
Anti-5-HT-2C antibody detects endogenous levels of total 5-HT-2C protein.
免疫原
The antiserum was produced against synthesized peptide derived from human 5-HT-2C.
Immunogen Range: 161-210
Immunogen Range: 161-210
生化/生理作用
In the nervous system, 5-HT-2C/HTR2C (5-hydroxytryptamine receptor 2C) participates in coordinating the intracellular responses to serotonin. It plays a major role in the modulation of energy homeostasis.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Gene structure and expression of serotonin receptor HTR2C in hypothalamic samples from infanticidal and control sows
Quilter CR, et al.
BMC Neuroscience (2012)
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis
Xu Y, et al.
Neuron, 60(4), 582-589 (2008)
Rajat K Das et al.
Respiratory physiology & neurobiology, 260, 105-113 (2018-11-18)
Hypoglossal (XII) motoneurons are activated by type 2 receptors for serotonin (5-HT). This activation is especially strong during wakefulness which facilitates diverse motor functions of the tongue, including the maintenance of upper airway patency in obstructive sleep apnea (OSA) patients.
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