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Merck

S3147

Sigma-Aldrich

5-磺基水杨酸 二水合物

suitable for electrophoresis, ≥99%

别名:

2-羟基-5-磺基苯甲酸

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100 G
$118.00
500 G
$279.00

About This Item

线性分子式:
HO3SC6H3-2-(OH)CO2H·2H2O
CAS号:
分子量:
254.21
Beilstein:
650741
EC號碼:
MDL號碼:
分類程式碼代碼:
41105319
PubChem物質ID:
NACRES:
NB.22

$118.00


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品質等級

化驗

≥99%

形狀

powder or crystals

技術

electrophoresis: suitable

雜質

≤0.02% Insoluble matter
≤0.05% Salicylic Acid

mp

105-110 °C (lit.)

溶解度

water: soluble 100 mg/mL, clear, colorless

負離子痕跡

chloride (Cl-): ≤0.001%
sulfate (SO42-): ≤0.035%

正離子痕跡

Fe: ≤0.001%
heavy metals (as Pb): ≤0.002%

SMILES 字串

[H]O[H].[H]O[H].OC(=O)c1cc(ccc1O)S(O)(=O)=O

InChI

1S/C7H6O6S.2H2O/c8-6-2-1-4(14(11,12)13)3-5(6)7(9)10;;/h1-3,8H,(H,9,10)(H,11,12,13);2*1H2

InChI 密鑰

BHDKTFQBRFWJKR-UHFFFAOYSA-N

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一般說明

5-磺基水杨酸是一种能够使水质子化的强酸。[1] 它可形成一种新的茶碱复合物,其已通过X射线光电子能谱(XPS)进行了研究。[2] 它可与-取代的单环杂芳族路易斯碱形成1:1的质子转移化合物。他们的晶体结构已经过研究。[1]

應用

5-磺基水杨酸二水合物可用于通过HPLC对衍生自聚乙二醇化脂质体多柔比星(Doxil)及其在人血浆中的主要代谢物中的多柔比星进行定量。[3] 它可用于制备聚[[三(二-2-吡啶基胺)三([ μ]-5-磺基水杨酸)三萜(II)]三水合物]。[4]
溶于12%三氯乙酸中的5-磺基水杨酸(3.5%)溶液通常用作琼脂糖和聚丙烯酰胺凝胶中蛋白质的固定液。

分析報告

已针对用于 PAGE、SDS-PAGE 和 IEF 的固定液而进行了测试。

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1 - Skin Corr. 1B

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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David L Chin et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 779(2), 259-269 (2002-10-04)
A high-performance liquid chromatographic method was developed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma. This method utilizes Triton X-100 to disperse the liposome, followed by a protein precipitation step
Hui Wang et al.
Frontiers in physiology, 11, 655-655 (2020-07-01)
Serotonin (5-HT), a monoaminergic neurotransmitter, involves in the regulation of many physiological functions. In the present study, the effects of 5-hydroxytryptophan (5-HTP), the precursor of 5-HT, on lipid metabolism and intestinal immune function in broiler chickens were investigated in chickens.
Joanna S Stevens et al.
The journal of physical chemistry. B, 114(44), 13961-13969 (2010-10-22)
Recent studies suggested that X-ray photoelectron spectroscopy (XPS) sensitively determines the protonation state of nitrogen functional groups in the solid state, providing a means for distinguishing between co-crystals and salts of organic compounds. Here we describe how a new theophylline
Megan A Dickson et al.
Reproductive biology and endocrinology : RB&E, 18(1), 49-49 (2020-05-16)
Cigarette smokers have a reduced risk of developing preeclampsia, possibly attributed to an increase in carbon monoxide (CO) levels. Carbon monoxide is a gasotransmitter that has been implicated in maintaining vascular tone, increasing angiogenesis, and reducing inflammation and apoptosis at
Hydrogen bonding in proton-transfer compounds of 5-sulfosalicylic acid with ortho-substituted monocyclic heteroaromatic Lewis bases.
Smith G, et al.
Journal of Chemical Crystallography, 36(12), 841-849 (2006)

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