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Merck

T0699

Sigma-Aldrich

三氯乙酸 溶液

6.1 N

别名:

TCA

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100 ML
$169.00

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100 ML
$169.00

About This Item

线性分子式:
Cl3CCOOH
CAS号:
分子量:
163.39
Beilstein:
970119
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.26

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形狀

liquid

品質等級

濃度

6.1 N
~100 % (w/v)

SMILES 字串

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI 密鑰

YNJBWRMUSHSURL-UHFFFAOYSA-N

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一般說明

三氯乙酸(TCA)是一种强酸。在饮用水pH值下,三氯乙酸呈现盐形式。

應用

三氯乙酸的应用示例:
  • 用于吲哚胺2,3-双加氧酶(IDO)活性测定,水解N-甲酰犬尿氨酸并生成犬尿氨酸
  • 用于人肺动脉平滑肌细胞(HPASMCs)增殖
  • 在蛋白提取和定量时,处理研磨组织和沉淀蛋白

生化/生理作用

三氯乙酸(TCA)全身性无毒,长久以来被用作浅表脱皮试剂。可用作过氧化物酶体增殖剂。
三氯乙酸溶液一般用于沉淀蛋白。可用于通过定量沉淀法测定蛋白浓度。三氯乙酸也可用作显微脱钙剂和固定剂。

訊號詞

Danger

危險聲明

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Guillaume Laflamme et al.
Cell reports, 26(11), 2875-2889 (2019-03-14)
The segregation of chromosomes is a critical step during cell division. This process is driven by the elongation of spindle microtubules and is tightly regulated by checkpoint mechanisms. It is unknown whether microtubules affect checkpoint responses as passive contributors or
Alan Mortensen et al.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 18(1), 55-62 (2012-10-17)
The ratio of the nitric oxide synthase (NOS) cofactor tetrahydrobiopterin (BH(4)) to its oxidized form dihydrobiopterin (BH(2)) has been suggested as an index of endothelial dysfunction. Consequently, much effort has been put into preserving the in vivo equilibrium between these
Valentina Folgiero et al.
Oncotarget, 5(8), 2052-2064 (2014-06-07)
Microenvironmental factors contribute to the immune dysfunction characterizing acute myeloid leukemia (AML). Indoleamine 2,3-dioxygenase 1 (IDO1) is an interferon (IFN)-γ-inducible enzyme that degrades tryptophan into kynurenine, which, in turn, inhibits effector T cells and promotes regulatory T-cell (Treg) differentiation. It
Hikmat Al-Ahmadie et al.
Cancer discovery, 4(9), 1014-1021 (2014-06-18)
Metastatic solid tumors are almost invariably fatal. Patients with disseminated small-cell cancers have a particularly unfavorable prognosis, with most succumbing to their disease within two years. Here, we report on the genetic and functional analysis of an outlier curative response
Emil D Bartels et al.
Circulation research, 117(11), 933-942 (2015-09-12)
Plasma cholesterol lowering is beneficial in patients with atherosclerosis. However, it is unknown how it affects entry and degradation of low-density lipoprotein (LDL) particles in the lesioned arterial wall. We studied the effect of lipid-lowering therapy on LDL permeability and

实验方案

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

This procedure may be used for determination of Pepsin activity using hemoglobin as the substrate. It is a spectrophotometric stop rate determination.

本方法可用于以血红蛋白为底物的胃蛋白酶活性测定。这是一种分光光度速率终止测定法。

This procedure may be used for the determination of Amyloglucosidase activity using starch as the substrate.

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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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