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Merck

P8813

Sigma-Aldrich

普罗替林 盐酸盐

≥99% (TLC), powder

别名:

N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride

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About This Item

经验公式(希尔记法):
C19H21N · HCl
CAS号:
分子量:
299.84
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

方案

≥99% (TLC)

表单

powder

颜色

white to off-white

溶解性

H2O: 50 mg/mL

SMILES字符串

Cl[H].CNCCCC1c2ccccc2C=Cc3ccccc13

InChI

1S/C19H21N.ClH/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18(16)19;/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3;1H

InChI key

OGQDIIKRQRZXJH-UHFFFAOYSA-N

基因信息

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生化/生理作用

Norepinephrine uptake blocker.

特点和优势

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

注意

Shelf-life of the powder is at least three years at room temperature.

象形图

Skull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M M Makhay et al.
Pharmacology, biochemistry, and behavior, 63(2), 319-324 (1999-06-17)
The ability of indirectly acting agonists such as norepinephrine uptake inhibitors, serotonin reuptake inhibitors, and atypical antidepressants to substitute for clenbuterol, a beta-2 adrenergic agonist, was examined in rats trained to discriminate 0.03 mg/kg clenbuterol and saline using a fixed-ratio
K Ström et al.
The European respiratory journal, 8(3), 425-429 (1995-03-01)
A daily dose of 20 mg of protriptyline can improve daytime arterial blood gas tensions in chronic obstructive pulmonary disease (COPD). Its usefulness is limited by anticholinergic side-effects. This study examined whether a daily dose of 10 mg of protriptyline
G M Barthlen
Respiration; international review of thoracic diseases, 64 Suppl 1, 35-38 (1997-01-01)
Patients with neuromuscular disease may suffer from nocturnal respiratory failure despite normal daytime respiratory function. The physiological reduction in muscle tone during sleep may be life-threatening in a patient with impaired muscle strength. Nocturnal respiratory failure may occur in patients
G L Cohen
Headache, 37(7), 433-436 (1997-07-01)
Twenty-five women with chronic tension-type headaches were treated with protriptyline for 3 months, with attention paid to days of monthly headaches before and while taking the medication, as well as change in weight and side effects. One patient stopped the
Anticholinergic delirium possibly associated with protriptyline and fluoxetine.
K L Paul et al.
The Annals of pharmacotherapy, 31(10), 1260-1261 (1997-10-24)

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