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Merck

O5500

Sigma-Aldrich

四氧化锇

Sealed ampule.

别名:

“锇酸", 氧化锇(VIII)

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About This Item

线性分子式:
OsO4
CAS号:
分子量:
254.23
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47

蒸汽密度

8.8 (vs air)

蒸汽壓力

7 mmHg ( 20 °C)

形狀

powder

反應適用性

reagent type: oxidant

bp

130 °C (lit.)

mp

39.5-41 °C (lit.)

SMILES 字串

O=[Os](=O)(=O)=O

InChI

1S/4O.Os

InChI 密鑰

VUVGYHUDAICLFK-UHFFFAOYSA-N

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相关类别

一般說明

四氧化锇(OsO4)是四面体构型的对称分子,含有第三过渡系过渡金属锇。四氧化锇可作为电镜的染料和非凝固型固定剂,主要用于组织病理学实验室中的生物组织检测。标本用四氧化锇再固定(postfix)可确保脂质保存。

應用

四氧化锇已作为固定剂用于短杆菌Brevibacterium mcbrellneri处理,以及经姜黄素处理的人癌细胞系的扫描电镜观察。还可作为固定剂用于弓形虫Toxoplasma gondii骨骼肌的超微结构分析。

生化/生理作用

四氧化锇化学性结合脂质,使其不溶;固定后仅余7%的脂质可提取。因此,用四氧化锇固定后,由磷脂组成的细胞膜会变黑且电子密度提高。它还可在石蜡处理过程中固定切片中的少量脂肪。

其他說明

由于四氧化锇的危害性,建议在使用该化学品时使用安瓿开启器。

象形圖

Skull and crossbonesCorrosion

訊號詞

Danger

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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