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一般描述
Microsomes are the fraction of "submicroscopic” particles isolated from homogenates of liver and other tissues. Microsomes are rich in ribonucleic acid (RNA).[1]
应用
生化/生理作用
肝微粒体是来源于肝细胞内质网的亚细胞颗粒。这些微粒体是药物代谢酶（包括细胞色素 P-450）的丰富来源。不同来源的微粒体池有助于研究外源代谢和药物相互作用。
药物代谢酶的来源，包括细胞色素 P-450。
Microsomes might act as cell organelles and are actively involved in protein synthesis.[1] Carbon monoxide-binding pigment of microsomes, named P-450, is an integral element of mixed function oxidase systems involved in the oxidative demethylation and hydroxylation of drugs and steroids.[4] Murine liver microsomes plays a crucial role in degradation of small antimicrobial β2,2-amino acid derivatives.[3]
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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Metabolism of small antimicrobial ?(2,2)-amino acid derivatives by murine liver microsomes.
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Role of hemoprotein P-450 in fatty acid omega-hydroxylation in a soluble enzyme system from liver microsomes.
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The Journal of Biological Chemistry, 243(6), 1331-1332 (1968)
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