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Merck

S2442

Sigma-Aldrich

S9 from Liver, Pooled

from human

别名:

Liver S9 Fraction, S9 Liver Extract

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About This Item

分類程式碼代碼:
12161501
NACRES:
NA.47

生物源

human

品質等級

包裝

vial of ~20 mg

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−70°C

基因資訊

human ... RPS9(6203)

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應用

Pooled S9 fractions from liver have been used for genotoxicity experiments.

生化/生理作用

The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. They are known to be a rich source of drug metabolizing enzymes including P-450. S9 pools are useful in the study of xenobiotic metabolism and drug interactions. They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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A conjugate of pyridine-4-aldoxime and atropine as a potential
antidote against organophosphorus compounds poisoning
Jasna Lovric
Acta Biochimica Polonica, 58(2) (2011)
The Ames Salmonella/microsome mutagenicity assay.
Mortelmans K and Zeiger E
Mutation Research (2000)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 169-172 (2001)
Marina Paul et al.
Reproductive sciences (Thousand Oaks, Calif.) (2023-02-11)
The mechanism by which human labor is initiated in the presence of elevated circulating progesterone levels remains unknown. Recent evidence indicates that the progesterone-metabolizing enzyme, 20α-hydroxysteroid dehydrogenase (20α-HSD), encoded by the gene AKR1C1, may contribute to functional progesterone withdrawal. We
Implementation of the Three Rs in the Human Hazard
Assessment of Brazilian Medicinal Plants: An Evaluation
of the Cytotoxic and Genotoxic Potentials of Dipteryx
alata Vogel
Natalia M. Esteves-Pedro
Alberta RN / Alberta Association of Registered Nurses (2011)

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