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生物源
bovine colostrum
品質等級
化驗
≥85% (SDS-PAGE)
形狀
powder
分子量
~90 kDa
技術
electrophoresis: suitable
ion chromatography: suitable
雜質
salt, essentially free
溶解度
H2O: soluble 5 mg/mL
UniProt登錄號
儲存溫度
2-8°C
基因資訊
cow ... LTF(280846)
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應用
生化／生理作用
乳铁蛋白是一种铁结合蛋白。 它的结构与转铁蛋白类似，即血浆铁转运蛋白；但乳铁蛋白对铁的亲和力要高得多（250倍）。它在初乳中的含量非常高，并且在泪液、唾液、粘液分泌物和中性粒细胞的次级颗粒中也少量存在。它由粘膜上皮和嗜中性粒细胞产生，由这些细胞在炎症刺激下释放。乳铁蛋白可以通过与铁螯合而抑制细菌生长，并且通过其N-末端与脂多糖结合而增加细菌细胞壁通透性。乳铁蛋白可以通过与病毒包膜蛋白紧密结合而抑制病毒感染。这能够阻断细胞与病毒的结合域，从而防止细胞-病毒融合。乳铁蛋白可能通过刺激白细胞介素-8（一种中性粒细胞激活剂）的释放而激活宿主防御系统。 它还可能参与抗体和白细胞介素合成、淋巴细胞增殖和补体激活。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Structural and functional characteristics of bovine milk protein glycosylation
O Riordan N, et al.
Glycobiology, 24(3), 220-236 (2014)
Isolation of lactoferrin from bovine colostrum by ultrafiltration coupled with strong cation exchange chromatography on a production scale
Lu RR, et al.
Journal of Membrane Science , 297(1-2), 152-161 (2007)
Erika N Biernbaum et al.
JDS communications, 2(3), 92-97 (2021-03-12)
Improper storage conditions or processing of milk leads to potential spoilage and illness, due in part to temperature abuse, allowing bacteria present to grow and spoil the product. However, certain proteins naturally found in raw milk, such as lactoferrin, have
Andrew S Cooke et al.
PeerJ, 8, e8631-e8631 (2020-05-06)
Promoting and maintaining health is critical to ruminant welfare and productivity. Within human medicine, faecal lactoferrin is quantified for routine assessment of various gastrointestinal illnesses avoiding the need for blood sampling. This approach might also be adapted and applied for
Serena Belegrinou et al.
Langmuir : the ACS journal of surfaces and colloids, 24(14), 7251-7261 (2008-06-14)
The interaction of the proteins bovine serum albumin (BSA), lysozyme (Lys), lactoferrin (Lf), and fibronectin (Fn) with surfaces of protein-resistant poly(ethylene oxide) (PEO) and protein-adsorbing poly(acrylic acid) (PAA) fabricated by plasma-enhanced chemical vapor deposition has been studied with quartz crystal
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