跳转至内容
Merck

L137

Sigma-Aldrich

L-733,060 hydrochloride

solid, ≥98% (HPLC)

别名:

(2S,3S)-3-[(3,5-bis(Trifluoromethyl)phenyl)methoxy]-2-phenylpiperidine hydrochloride

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C20H19F6NO · HCl
分子量:
439.82
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:

化驗

≥98% (HPLC)

形狀

solid

顏色

white

溶解度

DMSO: >10 mg/mL
H2O: insoluble

儲存溫度

2-8°C

SMILES 字串

Cl[H].FC(F)(F)c1cc(CO[C@@H]2CCCN[C@@H]2c3ccccc3)cc(c1)C(F)(F)F

基因資訊

human ... TACR1(6869)

生化/生理作用

Non-peptide NK1 tachykinin receptor antagonist; selective for guinea pig/human versus rat/mouse. Micromolar concentrations of L-733,060 inhibit the growth of human gastric and colon adenocarcinomas.in a dose-dependent manner, eventually leading to apoptosis in both cell lines.

法律資訊

Manufactured and sold under license from Merck & Co., Inc., Kenilworth, NJ, U.S.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

P Kiatpapan et al.
Journal of bioscience and bioengineering, 92(5), 459-465 (2005-10-20)
To develop systems for the expression of heterologous genes in probiotic strains of Lactobacillus and Propionibacterium, we used Lactobacillus plantarum and Propionibacterium freudenreichii and a modified gene encoding cholesterol oxidase (choA) from Streptomyces sp. to generate working models. The acetyl
Jitka Myskova et al.
Journal of medical entomology, 45(1), 133-138 (2008-02-21)
Quantification of Leishmania parasites in the sand fly digestive tract is important for evaluation of vector competence. We compared quantitative polymerase chain reaction (Q-PCR) with two "traditional" methods, estimation in situ and direct counting with the aid of a hemocytometer
Y Kaneko et al.
Journal of bioscience and bioengineering, 89(1), 62-67 (2005-10-20)
Lactobacillus plantarum NC13, a strain derived from the L. plantarum strain L137 isolated from a traditional fermented food produced in the Philippines, contains 9 of the 15 plasmids in the parental strain. To construct a shuttle vector between L. plantarum
Jong-Hyun Kim et al.
Journal of bioscience and bioengineering, 107(2), 124-129 (2009-02-17)
A gene (apuA) encoding amylopullulanase from a starch-hydrolyzing lactic acid bacterium, Lactobacillus plantarum L137, which had been isolated from traditional fermented food made from fish and rice in the Philippines, was found to contain two unique amino acid repeating units
Marisa Rosso et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 29(4), 245-254 (2008-09-11)
It has been demonstrated that substance P (SP) and neurokinin-1 (NK-1) receptor antagonist L-733,060 induces cell proliferation and inhibition, respectively, in several human cancer cell lines. At present, it is unknown whether such actions are exerted on human gastric and

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门