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This material should be stored refrigerated temperature at 2 - 8 °C. The product is assigned a retest date of approximately 2 years from the date of Quality release. The quality of this item cannot be quatanteed if stored outside of the recommended conditions for extended periods. Please see the link below to review the lot specific Certificate of Analysis to determine retest date:
https://www.sigmaaldrich.com/product/sigma/h8502#product-documentation
H8502
盐酸多巴胺 盐酸盐
≥98% (TLC), powder, neurotransmitter
别名:
2-(3,4-二羟基苯基)乙胺 盐酸盐, 3,4-二羟基苯乙胺 盐酸盐, 4-(2-氨乙基)-1,2-苯二醇 盐酸盐, 羟酪胺 盐酸盐
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5 G
$102.00
10 G
$192.00
25 G
$269.00
100 G
$1,050.00
About This Item
线性分子式:
(HO)2C6H3CH2CH2NH2·HCl
CAS号:
分子量:
189.64
Beilstein:
3656720
EC號碼:
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.77
推荐产品
产品名称
盐酸多巴胺 盐酸盐,
形狀
powder
品質等級
顏色
light tan
mp
248-250 °C (lit.)
溶解度
alcohol: 20 mg/mL
H2O: soluble
儲存溫度
2-8°C
SMILES 字串
Cl[H].NCCc1ccc(O)c(O)c1
InChI
1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H
InChI 密鑰
CTENFNNZBMHDDG-UHFFFAOYSA-N
基因資訊
human ... ADRB1(153)
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訊號詞
Warning
危險聲明
危險分類
Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 1
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Dopamine depresses the immune ability and increases susceptibility to Lactococcus garvieae in the freshwater giant prawn, Macrobrachium rosenbergii.
Li JT et al.
Fish & Shellfish Immunology, 19, 269-269 (2005)
Flow injection with inhibited chemiluminescence method for the determination of dopamine hydrochloride.
Shuhao WANG et al.
Analytical Sciences, 20, 315-317 (2004)
Y Luo et al.
The Journal of biological chemistry, 273(6), 3756-3764 (1998-03-07)
Dopamine (DA) is a neurotransmitter, but it also exerts a neurotoxic effect under certain pathological conditions, including age-related neurodegeneration such as Parkinson's disease. By using both the 293 cell line and primary neonatal rat postmitotic striatal neuron cultures, we show
Rafael Franco et al.
Biomedicines, 9(2) (2021-01-28)
Dopamine is derived from an amino acid, phenylalanine, which must be obtained through the diet. Dopamine, known primarily to be a neurotransmitter involved in almost any higher executive action, acts through five types of G-protein-coupled receptors. Dopamine has been studied
Peripheral Dopamine Controlled by Gut Microbes Inhibits Invariant Natural Killer T Cell-Mediated Hepatitis
Xue R, et al.
Frontiers in Immunology, 9, 2398-2398 (2018)
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DISCOVER Bioactive Small Molecules for Neuroscience
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How long can it be stored? I found two in our lab, but one at room temperature for years and another one in 10 oC fridge.
1 answer-
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Upon dissolving the H8502 powder, the solution turned dark purple/black. What could be the cause of this discoloration? Can the product still be considered suitable for use?
Upon dissolving the H8502 powder, the solution turned dark purple/black. What could be the cause of this discoloration? Can the product still be considered suitable for use?
1 answer-
Regarding the solubility of product H8502, it can be dissolved in alcohol at a concentration of 20 mg/mL or in water (H2O) at 100 mg/mL. It is recommended that solutions be prepared fresh and not stored for long-term use. Preparing aliquots for storage at -20°C or keeping the product in solution at 4-8°C is not advised.
Dopamine, the active component, is sensitive to light and the free base form is particularly prone to oxidation. Solutions with a pH range of 5.4 to 6.8 have been reported to remain stable for a maximum of 48 hours at 25°C, beyond which the solution may darken and become unusable.
Dopamine solutions should not be mixed with alkalis, iron salts, or oxidizing agents, and are known to be incompatible with certain antibiotics, including amphotericin, ampicillin, gentamicin sulfate, and benzylpenicillin.
In the literature, you can find some articles where the stability of this compound is indicated. For example: https://www.ncbi.nlm.nih.gov/pubmed/14651669
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Is this product analytical standard that can be used in LCMSMS to quantify the amount of Dopamine?
1 answer-
Unfortunately, this product is not tested as an analytical standard for use in LCMSMS.
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Can it be stored at -20C
1 answer-
The recommended storage temperature for this product is 2-8°C. In general, powder materials are not affected by freezer storage, however, this item has not been tested under these storage conditions.
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