G9880

谷丙转氨酶 来源于猪心脏

ammonium sulfate suspension, ≥75 units/mg protein

• 别名: L-丙氨酸:2-酮戊二酸氨基转移酶, GPT, 丙氨酸氨基转移酶（催化浓度）
• CAS号: 9000-86-6
• EC 号: 2.6.1.2 (BRENDA, IUBMB)
• Beilstein: 3562140
• EC 号: 232-561-4
• MDL编号: MFCD00131192
• UNSPSC代码: 12352204
• NACRES: NA.54

属性

• 生物来源: Porcine heart
• 质量水平: 200
• 表单: ammonium sulfate suspension
• 比活: ≥75 units/mg protein
• 分子量: 42 kDa
• 异质活性: L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%; glutamic-oxalacetic transaminase ≤0.05%
• 运输: wet ice
• 储存温度: 2-8°C

说明

一般描述

Research area: Cell Signaling
Glutamic-pyruvic transaminase (GPT) is located in most cells in the body but is found in highest concentrations in the liver. Two GPT isoforms, GPT1 and GPT2, are present in mammals.[1]

应用

Glutamic-Pyruvic Transaminase from porcine heart has been used to determine L-lactate levels in aqueous polyethylene glycol (PEG) solutions. [2][3][4]

生化/生理作用

GPT is responsible for catalyzing the reversible transamination of α-ketoglutarate and alanine to glutamate and pyruvate. It also plays a critical role in the metabolism of amino acids and gluconeogenesis.[1]

谷丙转氨酶 (GPT) 存在于体内大多数细胞中，但在肝脏中浓度最高。由于在肝细胞坏死后 GPT 释放入血液，可作为肝脏疾病的标志物。

单位定义

一个单位在37℃和pH 7.6，L-丙氨酸存在条件下将1.0μmole α酮戊二酸转化成L-谷氨酸。

外形

1.8M (NH₄)₂SO₄ 溶液中的悬浮液，pH 6.0

分析说明

由缩二脲确定的蛋白质。

安全信息

• 象形图: GHS08
• 警示用语：: Danger
• 危险声明: H334
• 预防措施声明: P261 - P284 - P501
• 危险分类: Resp. Sens. 1
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)