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一般描述
Gc-球蛋白(来自人血浆)由定位至人类染色体4q13.3上的基因所编码。[3]
Gc-球蛋白,白蛋白超家族成员,是维生素D及其代谢物主要的血浆载体。 还与凝溶胶蛋白共同服务于胞外肌动蛋白清除系统。 Gc-球蛋白也能高亲和地结合肌动蛋白单体(G-肌动蛋白),清除坏死细胞释放的肌动蛋白,防止其聚合成为肌丝。 Gc球蛋白可增强C5a对炎性细胞的趋化作用。
应用
Gc-球蛋白是多功能的白蛋白样血浆蛋白,通常需要结合到细胞表面才能发挥多样功能。[4] 本品已用于分析Gc-球蛋白的糖基化模式。
生化/生理作用
GC基因的单核苷酸多态性与25-羟基维生素D[25(OH)D]的缺乏相关。[3]
Gc-球蛋白,白蛋白超家族成员,是维生素D及其代谢物主要的血浆载体。还协同凝溶胶蛋白服务于胞外肌动蛋白清除系统。Gc-球蛋白也能高亲和地结合肌动蛋白单体(G-肌动蛋白),清除坏死细胞释放的肌动蛋白,防止其聚合成为肌丝。Gc球蛋白可增强C5a对炎性细胞的趋化作用。
制备说明
来自人血浆的天然Gc-球蛋白
免责声明
仅供研究使用。本品在法国的科研应用受到监管,包括用于进口和出口活动(法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2)。如《公共卫生法典》所述,购买者(即最终用户)需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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