G5640

Globulins Cohn fraction II, III 来源于山羊

• 别名: Vitamin D binding protein
• CAS号: 68476-36-8
• EC號碼: 270-678-2
• MDL號碼: MFCD00164084
• 分類程式碼代碼: 12352202
• NACRES: NA.61

属性

• 生物源: goat
• 化驗: 73-90% protein basis (biuret)
• 形狀: lyophilized powder
• 成份: Protein, 73-90% biuret
• 溶解度: H₂O: soluble 25 mg/mL
• 儲存溫度: 2-8°C

说明

一般說明

Vitamin D binding protein (DBP) is a polymorphic protein that specifically binds to vitamin D and its metabolites. This protein belongs to the albuminoid family and is highly conserved among vertebrates. The gene encoding DBP is mapped to human chromosome 4q11-q13. It is predominantly produced in the liver and is also expressed in the kidney, endocrine pancreatic cells, fat cells, and testis.

應用

Globulins were used in Biotin/avidin formulations.

生化／生理作用

Vitamin D binding protein (DBP) specifically binds and transports vitamin D and its metabolites with high affinity. It promotes fibrillar actin clearance by binding to actin monomers. DBP also binds to unsaturated fatty acids, megalin-cubilin receptor complex, the membrane of leukocytes, and the activation of the complement C5 system. The levels of DBP indicate the free concentration of all vitamin D metabolites. Decreased levels of serum DBP are observed in liver diseases, nephrotic syndrome, malnutrition, severe acute trauma, or disease.

其他說明

Primarily γ-globulins

外觀

Lyophilized powder containing NaCl

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable