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品質等級
化驗
≥99% (HPLC)
形狀
powder
溶解度
water: 50 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
O.[Na+].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP(O)([O-])=O)O3)C(=O)N1
InChI
1S/C10H14N5O7P.Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;1H2/q;+1;/p-1/t4-,5+,6+;;/m0../s1
InChI 密鑰
UVKXYXSKMTUDML-FVALZTRZSA-M
應用
2′-脱氧鸟苷5′-单磷酸酯(dGMP)用作鸟苷酸激酶(EC 2.7.4.8)的底物,形成dGDP,磷酸化为dGTP后可支持DNA生物合成。dGMP用于研究鸟嘌呤类分子的理化特性。
2′-脱氧鸟苷5′-单磷酸钠盐水合物已被用于:
- 反相高压力液相色谱(HPLC)分析
- 确定脱氧单核苷酸对自发增殖的CaCo-2细胞系的影响
- 确定其刺激免疫细胞生长和功能的能力,并在体外使用流行性感冒病毒抗原作为免疫刺激剂
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
其他客户在看
Molecular and biochemical parasitology, 159(2), 130-133 (2008-04-01)
The present work describes cloning, expression, purification, characterization, and mutation of Plasmodium falciparum guanylate kinase (PlasmoDB ID PFI1420w). Amino-acid sequence alignment revealed important differences especially in K42-V51, Y73-A77, and F100-L110, which include residues important for kinase activity, and at helix
Biochemical pharmacology, 81(1), 43-49 (2010-09-18)
Many fraudulent nucleosides including the antivirals acyclovir (ACV) and ganciclovir (GCV) must be metabolized to triphosphates to be active. Cyclopropavir (CPV) is a newer, related guanosine nucleoside analog that is active against human cytomegalovirus (HCMV) in vitro and in vivo.
Dietary nucleotides and human immune cells. II. Modulation of PBMC growth and cytokine secretion
Nutrition, 22(1), 90-96 (2006)
Roumanian archives of microbiology and immunology, 66(1-2), 22-25 (2008-10-22)
Guanylate kinase is a member of the nucleoside monophosphate (NMP) kinase family, a family of enzymes that despite having a low primary structure identity share a similar fold, which consists of three structurally distinct regions termed the CORE, LID, and
Journal of molecular recognition : JMR, 24(2), 322-332 (2011-03-02)
Plasmodium deoxyguanylate pathways are an attractive area of investigation for future metabolic and drug discovery studies due to their unique substrate specificities. We investigated the energetic contribution to guanylate kinase substrate binding and the forces underlying ligand recognition. In the
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