推荐产品
生物源
microbial (fermentation)
等級
Sigma Grade
化驗
≥98%
形狀
powder
儲存溫度
−20°C
SMILES 字串
[Na].NC1=NC(=O)N(C=C1)C2CC(O)C(COP(O)(O)=O)O2
InChI
1S/C9H14N3O7P.Na.H/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(19-8)4-18-20(15,16)17;;/h1-2,5-6,8,13H,3-4H2,(H2,10,11,14)(H2,15,16,17);;
InChI 密鑰
BLEUYVBRJBDVEH-UHFFFAOYSA-N
相关类别
應用
2′-脱氧胞苷-5′-单磷酸钠盐已被用于:
- 肾细胞癌(RCC)细胞SN12C的核苷稳定性研究
- 人肠道Caco-2细胞系和外周血单核细胞(PBMC)的细胞增殖研究
- 作为dsDNA激活诱导的胞苷脱氨酶结晶中的配体
将2′-脱氧胞苷-5-单磷酸(CMP)用作尿苷一磷酸(UMP)/胞苷一磷酸(CMP)激酶(EC 2.7.4.4)的底物以形成 dCDP,其在磷酸化至 dCTP 后,支持 DNA 和 RNA 生物合成。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer
Nature, 524(7563), 114-114 (2015)
Journal of molecular modeling, 14(5), 427-434 (2008-03-18)
Bacterial cytidylate kinase or cytidine monophosphate kinase (CMP kinase) catalyses the phosphoryl transfer from ATP to CMP and dCMP, resulting in the formation nucleoside diphosphates. In eukaryotes, CMP/UMP kinase catalyses the conversion of UMP and CMP to, respectively, UDP and
AID recognizes structured DNA for class switch recombination
Molecular Cell, 67(3), 361-373 (2017)
Molecular pharmacology, 67(3), 806-814 (2004-11-20)
Human UMP/CMP kinase (cytidylate kinase; EC 2.7.4.14) is responsible for phosphorylation of CMP, UMP, and deoxycytidine monophosphate (dCMP) and also plays an important role in the activation of pyrimidine analogs, some of which are clinically useful anticancer or antiviral drugs.
Dietary nucleotides and intestinal cell lines: I. Modulation of growth
Nutrition Research (New York, N.Y.), 24(3), 197-207 (2004)
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