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生物源
synthetic (organic)
化驗
≥98.5%
形狀
powder
雜質
Thymidine, free
溶解度
water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES 字串
OC[C@H]1O[C@H](C[C@@H]1O)N2C=CC(=O)NC2=O
InChI
1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1
InChI 密鑰
MXHRCPNRJAMMIM-SHYZEUOFSA-N
基因資訊
mouse ... Slc29a1(63959)
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應用
2′-脱氧尿苷已用于:
- 代替胸苷用作[3H]胸苷三磷酸 (TTP)前体,避免在相对增殖测定中潜在的胸苷阻断
- 用作核苷补充剂,以进行细胞周期同步和DNA复制抑制
- 用作培养基中的有丝分裂抑制剂,最大限度减少神经胶质细胞增殖
生化/生理作用
2′-脱氧尿苷(dU)经常被卤化,生成用于DNA合成和降解机制研究的胸苷激酶类似物。作为标记底物的衍生2′-脱氧尿苷包括氯-2′-脱氧尿苷(CldU)、溴脱氧尿苷(BrdU)和/或碘脱氧尿苷(IdU)。其他有用的2′-脱氧尿苷类似物包括5-乙基-2′-脱氧尿苷(DdU)和5-羟基甲基-2′-脱氧尿苷(HmdU)。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
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