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Merck

C7629

Sigma-Aldrich

L-瓜氨酸

≥98% (TLC)

别名:

L-2-氨基-5-脲基戊酸, (S)-2-氨基-5-脲基戊酸

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10 MG
$64.00
1 G
$103.00
5 G
$129.00
25 G
$294.00
100 G
$742.00
500 G
$2,980.00
1 KG
$4,470.00

$64.00


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变更视图
10 MG
$64.00
1 G
$103.00
5 G
$129.00
25 G
$294.00
100 G
$742.00
500 G
$2,980.00
1 KG
$4,470.00

About This Item

经验公式(希尔记法):
C6H13N3O3
CAS号:
分子量:
175.19
Beilstein:
1725416
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.32

$64.00


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获取大包装报价

产品名称

L-瓜氨酸, ≥98% (TLC)

质量水平

方案

≥98% (TLC)

表单

powder

颜色

white to off-white

应用

detection

SMILES字符串

N[C@@H](CCCNC(N)=O)C(O)=O

InChI

1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1

InChI key

RHGKLRLOHDJJDR-BYPYZUCNSA-N

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应用

L-瓜氨酸已用于超高效液相色谱中,以验证参与变质过程协调的代谢物。[1]

生化/生理作用

人们发现,口服L-瓜氨酸可改善人类镰状细胞疾病的状况。[2]在NO(一氧化氮)合成酶缺陷的情况下,可以服用L-瓜氨酸,替代L-精氨酸。人们发现,L-瓜氨酸补充剂能满足NO(一氧化氮)依赖型信号传导的目的。[3]
通过NO(一氧化氮)合成酶,从L-精氨酸生产一氧化氮的中间体。[4]

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
Hayashi T
Proceedings of the National Academy of Sciences of the USA null
Nu-Hydroxy-L-arginine Is an Intermediate in the Biosynthesis of Nitric Oxide from L-Arginin
Dennis J. Stuehr
The Journal of Biological Chemistry, 266, 6259-6263 (1991)
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.
Schwedhelm E
British Journal of Clinical Pharmacology, 65(1), 51-59 (2008)
P Crenn et al.
Gastroenterology, 119(6), 1496-1505 (2000-12-13)
No blood marker assessing the functional absorptive bowel length has been identified. Plasma citrulline, a nonprotein amino acid produced by intestinal mucosa, is one candidate. We tested this hypothesis in adult patients with the short-bowel syndrome, whose condition can lead
Ran Lin et al.
Molecular cell, 68(1), 198-209 (2017-10-07)
In addition to responding to environmental entrainment with diurnal variation, metabolism is also tightly controlled by cell-autonomous circadian clock. Extensive studies have revealed key roles of transcription in circadian control. Post-transcriptional regulation for the rhythmic gating of metabolic enzymes remains

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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