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Merck

75447

Sigma-Aldrich

2-氧代己二酸 单钠盐

≥95.0% (HPLC)

别名:

α-酮己二酸 单钠盐, 2-己二酸, 2-氧己二酸 单钠盐

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About This Item

经验公式(希尔记法):
C6H8O5
CAS号:
分子量:
160.12
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.25

化驗

≥95.0% (HPLC)
≥97.0% (T)

形狀

powder

脂質類型

saturated FAs

儲存溫度

2-8°C

SMILES 字串

OC(=O)CCCC(=O)C(O)=O

InChI

1S/C6H8O5/c7-4(6(10)11)2-1-3-5(8)9/h1-3H2,(H,8,9)(H,10,11)

InChI 密鑰

FGSBNBBHOZHUBO-UHFFFAOYSA-N

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相关类别

應用


  • Engineering of phenylalanine dehydrogenase from Thermoactinomyces intermedius for the production of a novel homoglutamate: Showcases the application of 2-oxoadipic acid in enzyme engineering, enhancing biocatalytic processes for the production of novel compounds, vital for pharmaceutical and chemical industries (Tariq et al., 2022).

生化/生理作用

TCA循环和赖氨酸生物合成之间的重要代谢物。 对于线粒体代谢物转运蛋白具有意义。

包裝

无底玻璃瓶。内含物在插入的融合锥体内。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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R Lukacin et al.
European journal of biochemistry, 249(3), 748-757 (1997-12-12)
Flavanone 3beta-hydroxylase, involved in the biosynthesis of flavonoids, catechins, and anthocyanidins, is a non-heme iron enzyme, dependent on Fe2+, molecular oxygen, 2-oxoglutarate, and ascorbate, the typical cofactors of the class of 2-oxoglutarate-dependent dioxygenases. Sequence alignment analysis of various 2-oxoglutarate-dependent dioxygenases
alpha-Aminoadipic and alpha-ketoadipic aciduria: detection of a new case by a screening program using two-dimensional thin layer chromatography of amino acids.
C Vianey-Liaud et al.
Journal of inherited metabolic disease, 8 Suppl 2, 133-134 (1985-01-01)
S A Osmani et al.
European journal of biochemistry, 147(1), 119-128 (1985-02-15)
Cell-free extracts of Rhizopus arrhizus contain exclusively cytosolic pyruvate carboxylase and NAD-glutamate dehydrogenase, a single mitochondrial isoenzyme of NADP-isocitrate dehydrogenase, and both mitochondrial and cytosolic isoenzymes of NADP-malate dehydrogenase (decarboxylating). Other enzymes examined have sub-cellular localisations similar to those characteristic
Iwona Gabriel et al.
FEMS yeast research, 13(2), 143-155 (2012-10-31)
The LYS12 gene from Candida albicans, coding for homoisocitrate dehydrogenase was cloned and expressed as a His-tagged protein in Escherichia coli. The purified gene product catalyzes the Mg(2+)- and K(+)-dependent oxidative decarboxylation of homoisocitrate to α-ketoadipate. The recombinant enzyme demonstrates
A patient with alpha-ketoadipic and alpha-aminoadipic aciduria.
M Duran et al.
Journal of inherited metabolic disease, 7(2), 61-61 (1984-01-01)

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