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Merck

75890

Sigma-Aldrich

α-酮戊二酸

α-Ketoglutaric acid

99.0-101.0% (T)

别名:

α-酮戊二酸, 2-氧代戊二酸, 2-氧化戊二酸

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25 G
$59.80
100 G
$175.00
500 G
$406.00

About This Item

线性分子式:
HOOCCH2CH2COCOOH
CAS号:
分子量:
146.10
Beilstein:
1705689
EC號碼:
MDL號碼:
分類程式碼代碼:
12352115
PubChem物質ID:
NACRES:
NA.22

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品質等級

化驗

99.0-101.0% (T)

形狀

crystals

mp

114-118 °C

溶解度

H2O: 1 g/10 mL, clear to slightly hazy, colorless to almost colorless

儲存溫度

2-8°C

SMILES 字串

OC(=O)CCC(=O)C(O)=O

InChI

1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)

InChI 密鑰

KPGXRSRHYNQIFN-UHFFFAOYSA-N

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一般說明

α-酮戊二酸是一种2-氧代羧酸(2-OCA),其在Kreb循环中作为代谢物产生。[1]

應用

α-酮戊二酸与 L-精氨酸可以用氰基硼氢化钠还原形成非对映异构体:胭脂碱和异吲哚。[2]

其他說明

分析色氨酸的试剂[3];谷氨酸脱氢酶的底物

象形圖

Corrosion

訊號詞

Danger

危險聲明

危險分類

Eye Dam. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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N. Anderson et al.
Journal of Food Science, 43, 1595-1595 (1978)
White biotechnology for green chemistry: fermentative 2-oxocarboxylic acids as novel building blocks for subsequent chemical syntheses
Stottmeister U, et al.
Journal of Industrial Microbiology & Biotechnology, 32(11-12), 651-664 (2005)
A useful synthesis of nopaline, a crown gall tumor metabolite
Jensen RE, et al.
Biochemical and Biophysical Research Communications, 75(4), 1066-1070 (1977)
Ewa Tomaszewska et al.
Animals : an open access journal from MDPI, 10(12) (2020-12-23)
The aim of the experiment was to assess the effect of dietary alpha-ketoglutarate (AKG) supplementation on performance, serum hormonal indices, duodenum and jejunum histomorphometry, meat quality characteristics, bone quality traits and cartilage degradation in laying hens with a mature skeletal
J Kitaura et al.
European journal of pediatrics, 158(5), 410-413 (1999-05-20)
Two cases of hyperinsulinaemic hypoglycaemia associated with persistent hyperammonaemia in unrelated infants of 7 days and 4 months of age are reported. Blood ammonia levels were 100-300 micromol/l (normal values <40 micromol/l). The hyperammonaemia was asymptomatic and not associated with

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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