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Merck

S5632

Supelco

磺胺甲二唑

analytical standard, ≥99% (HPLC)

别名:

4-氨基-N-(5-甲基-1,3,4-噻二唑-2-基)苯磺酰胺, N1-(5-甲基-1,3,4-噻二唑-2-基)磺胺

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25 G
$175.00

$175.00


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25 G
$175.00

About This Item

经验公式(希尔记法):
C9H10N4O2S2
CAS号:
分子量:
270.33
Beilstein:
255002
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

$175.00


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等级

analytical standard

质量水平

Agency

EPA 1694

方案

≥99% (HPLC)

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

clinical testing

包装形式

neat

储存温度

2-8°C

SMILES字符串

Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

InChI

1S/C9H10N4O2S2/c1-6-11-12-9(16-6)13-17(14,15)8-4-2-7(10)3-5-8/h2-5H,10H2,1H3,(H,12,13)

InChI key

VACCAVUAMIDAGB-UHFFFAOYSA-N

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一般描述

Sulfamethizole is an antibacterial drug [1][2] used in the treatment of the urinary tract infections.[3]

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfamethizole may be used as a reference standard to examine the antibiotic remnants in honey by multianalyte/multiclass ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) method.[4]

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Janez Seliger et al.
Physical chemistry chemical physics : PCCP, 12(40), 13007-13019 (2010-09-08)
The 1,3,4-thiadiazole derivatives (2-amino-1,3,4-thiadiazole, acetazolamide, sulfamethizole) have been studied experimentally in the solid state by (1)H-(14)N NQDR spectroscopy and theoretically by Density Functional Theory (DFT). The specific pattern of the intra and intermolecular interactions in 1,3,4-thiadiazole derivatives is described within
Stephen P Mezyk et al.
The journal of physical chemistry. A, 111(37), 9019-9024 (2007-08-25)
Absolute rate constants and degradation efficiencies for hydroxyl radical and hydrated electron reactions with four different sulfa drugs in water have been evaluated using a combination of electron pulse radiolysis/absorption spectroscopy and steady-state radiolysis/high-performance liquid chromatography measurements. For sulfamethazine, sulfamethizole
Coordination chemistry of sulfamethizole: crystal structures of [Cu (sulfamethizolate) 2 (py) 2 (OH 2)]? H 2 O,[M (sulfamethizolate) 2 (py) 2 (OH 2) 2][M= Co and Ni] and {Cu (sulfamethizolate) 2 (dmf) 2}?.
Borras E, et al.
Polyhedron, 19(15), 1859-1866 (2000)
Development of a rapid method for the determination of antibiotic residues in honey using UPLC-ESI-MS/MS.
Kivrak I, et al.
Food Sci. Technol., 36(1), 90-96 (2016)
Ali Md Ahad et al.
Bioorganic & medicinal chemistry, 19(6), 2046-2054 (2011-03-01)
Disruption of the phosphatidylinositol 3-kinase/AKT signaling pathway can lead to apoptosis in cancer cells. Previously we identified a lead sulfonamide that selectively bound to the pleckstrin homology (PH) domain of AKT and induced apoptosis when present at low micromolar concentrations.

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