PHR1397

氟轻松

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 氟轻松, 6α,9α-二氟-11β,16α,17α,21-四羟基-1,4-妊娠双烯-3,20-二酮, 6α,9α-二氟-16α-羟基泼尼松龙16,17-缩丙酮, 6α-氟代曲安奈德, 仙乃乐, 醋酸肤轻松
• 经验公式（希尔记法）: C₂₄H₃₀F₂O₆
• CAS号: 67-73-2
• 分子量: 452.49
• EC 号: 200-668-5
• MDL编号: MFCD00010525
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329823371
• NACRES: NA.24

属性

• 等级: certified reference material; pharmaceutical secondary standard
• 质量水平: 300
• Agency: traceable to BP 160; traceable to Ph. Eur. F0200000; traceable to USP 1275009
• API类: fluocinolone
• CofA: current certificate can be downloaded
• 技术: HPLC: suitable; gas chromatography (GC): suitable
• mp: 267-269 °C (lit.)
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• 储存温度: 2-30°C
• SMILES字符串: CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
• InChI: 1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
• InChI key: FEBLZLNTKCEFIT-VSXGLTOVSA-N
• 基因信息: human ... NR3C1(2908)

说明

一般描述

Fluocinolone Acetonide is a soluble potent steroid, approved for implantable corticosteroid devices named fluocinolone acetonide intravitreal implants for the treatment of chronic uveitis.[1][2]
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Fluocinolone Acetonide may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using differential-pulse polarography.[3]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA2173 in the slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H315,H319,H335
• 预防措施声明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危险分类: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 靶器官: Respiratory system
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable